2349-14-6Relevant articles and documents
Total Synthesis of (-)-Sinulariadiolide. A Transannular Approach
Meng, Zhanchao,Fürstner, Alois
supporting information, p. 805 - 809 (2019/01/23)
The constrained tricyclic skeleton of the nor-cembranoid sinulariadiolide (1) with a nine-membered nexus was obtained by a cascade of transannular Michael reaction, carbonate elimination, butenolide formation, and spontaneous oxa-Michael addition of MeOH. The required macrocyclic precursor was prepared by ring-closing alkyne metathesis followed by trans-hydrostannation/carbonylation.
Molecular iodine as efficient co-catalyst for facile oxidation of alcohols with hypervalent(III) iodine
Karade,Tiwari,Huple
, p. 2039 - 2042 (2007/10/03)
A simple and mild procedure for the facile oxidation of alcohols to ketones and acids using a catalytic quantity of molecular iodine in combination with (diacetoxyiodo)benzene in acetonitrile is described. Direct oxidative methyl esterification of alcohols is also reported in methanol as solvent. Oxidation of alcohols is induced by iodonium ion generated in situ by the chemical oxidation of molecular iodine with (diacetoxyiodo)benzene. Georg Thieme Verlag Stuttgart.
Nuclear Synthons: Mesyltriflone as an Olefin Polyanion Equivalent
Hendrickson, James B.,Boudreaux, Gerald J.,Palumbo, Paul S.
, p. 2358 - 2366 (2007/10/02)
Mesyltriflone (CF3SO2CH2SO2CH3) is developed as a nuclear synthon reagent capable first of multiple constructions such as alkylations then of Ramberg-Baecklund elimination to a substituted olefin.The alkylations are clean and regiospecific, often amenable to one-pot operation, and in most cases the elimination is smooth.A variety of examples is presented to establish the scope of the method, and the mechanism and stereochemistry are discussed.
