2349-14-6Relevant academic research and scientific papers
Total Synthesis of (-)-Sinulariadiolide. A Transannular Approach
Meng, Zhanchao,Fürstner, Alois
supporting information, p. 805 - 809 (2019/01/23)
The constrained tricyclic skeleton of the nor-cembranoid sinulariadiolide (1) with a nine-membered nexus was obtained by a cascade of transannular Michael reaction, carbonate elimination, butenolide formation, and spontaneous oxa-Michael addition of MeOH. The required macrocyclic precursor was prepared by ring-closing alkyne metathesis followed by trans-hydrostannation/carbonylation.
PLANT OR MICROORGANISM-DERIVED CAROTENOID-OXYGEN COPOLYMER COMPOSITIONS, METHODS OF IDENTIFYING, QUANTIFYING AND PRODUCING SAME AND USES THEREOF
-
, (2017/09/21)
The present invention relates to carotenoid-oxygen copolymers, compositions, methods of identifying and quantifying carotenoid-oxygen copolymers in food and related sources, and methods of producing compositions comprising same. In one aspect the method of identifying and quantifying carotenoid-oxygen copolymers comprises an analysis of a low molecular weight marker compound in said sources. In another aspect the present invention provides a method of preparing compositions comprising said carotenoid-oxygen copolymers and/or enhancing levels of said copolymers in food sources in a sufficient and practically useful concentration to have beneficial effects in animals and humans, including beneficial immunological and health effects.
Molecular iodine as efficient co-catalyst for facile oxidation of alcohols with hypervalent(III) iodine
Karade,Tiwari,Huple
, p. 2039 - 2042 (2007/10/03)
A simple and mild procedure for the facile oxidation of alcohols to ketones and acids using a catalytic quantity of molecular iodine in combination with (diacetoxyiodo)benzene in acetonitrile is described. Direct oxidative methyl esterification of alcohols is also reported in methanol as solvent. Oxidation of alcohols is induced by iodonium ion generated in situ by the chemical oxidation of molecular iodine with (diacetoxyiodo)benzene. Georg Thieme Verlag Stuttgart.
OZONOLYSIS OF ALKENES AND THE REACTIONS OF POLYFUNCTIONAL COMPOUNDS LIII.SYNTHESIS OF THE ESTERS OF 2,3-DIHYDRO DERIVATIVES OF TRI-, DI-, AND MONOPRENOIC ACIDS
Odinokov, V. N.,Kukovinets, O. S.,Sakharova, N. I.,Tolstikov, G. A.
, p. 24 - 30 (2007/10/02)
The esters of the 2,3-dihydro derivatives of geranylgeranic, farnesylic, and geranic acids (di-, sesqui-, and monoterpenoid acids) were synthesized from the products from ozonolysis of 1,5,9-trimethyl-1E,5E,9E-cyclododecatriene.
Nuclear Synthons: Mesyltriflone as an Olefin Polyanion Equivalent
Hendrickson, James B.,Boudreaux, Gerald J.,Palumbo, Paul S.
, p. 2358 - 2366 (2007/10/02)
Mesyltriflone (CF3SO2CH2SO2CH3) is developed as a nuclear synthon reagent capable first of multiple constructions such as alkylations then of Ramberg-Baecklund elimination to a substituted olefin.The alkylations are clean and regiospecific, often amenable to one-pot operation, and in most cases the elimination is smooth.A variety of examples is presented to establish the scope of the method, and the mechanism and stereochemistry are discussed.
OXIDATION OF α,β-UNSATURATED ALDEHYDES
Bal, Balkrishna S.,Childers, Wayne E.,Pinnick, Harold W.
, p. 2091 - 2096 (2007/10/02)
A variety of methods for the conversion of α,β-unsaturated aldehydes to the corresponding acids have been explored.The best approach uses sodium chlorite and gives the desired transformation even in systems where steric hindrance and/or sensitive functionality are present.
A NOVEL METHOD FOR THE TERPENE SYNTHESIS BY THE RING-OPENING REACTION OF β-METHYL-β-PROPIOLACTONE
Fujisawa, Tamotsu,Sato, Toshio,Kawara, Tatsuo,Noda, Atsunari,Obinata,Toshiyuki
, p. 2553 - 2554 (2007/10/02)
A new route for the terpene synthesis is investigated, which undergoes via terpene carboxylic acids as key intermediates obtained by the regiospecific ring opening of β-methyl-β-propiolactone with cuprate or with a Grignard reagent in the presence of a copper catalyst.
