2353-40-4Relevant academic research and scientific papers
Synthesis of 3-methylaspartic acids by ring-contraction of a nickelacycle derived from glutamic anhydride
Echavarren, Antonio M.,Castano, Ana M.
, p. 2369 - 2378 (1995)
The synthesis of protected methylaspartic acids from glutamic acid has been achieved by means of ring contraction of the derived nickelacycle followed by insertion of isocyanides.
Hydrolyzed metabolites of thalidomide: Synthesis and TNF-α production-inhibitory activity
Nakamura, Takanori,Noguchi, Tomomi,Miyachi, Hiroyuki,Hashimoto, Yuichi
, p. 651 - 654 (2008/02/08)
Putative hydrolyzed metabolites of thalidomide were prepared and characterized, and their inhibitory activity on tumor necrosis factor (TNF)-α production in the human monocytic leukemia cell line THP-1 was evaluated. α-(2-Carboxybenzamido)glutarimide was a more potent TNF-α production inhibitor than thalidomide.
