2357-14-4

Usage

Structure

A biphenyl core with four fluorine atoms attached to different positions on the phenyl rings.

Type

Fluorinated biphenyl

Applications

Starting material for the synthesis of various organic compounds
Key building block in the production of liquid crystals and other advanced materials
Component in the development of semiconductors and electronic devices
Utilized in medicinal chemistry for the design and synthesis of biologically active compounds

Properties

High thermal stability
Unique electronic properties

Versatility

Wide range of applications in research, industry, and technology.

Upstream product

• 363-72-4 Pentafluorobenzene 
• 94-36-0 dibenzoyl peroxide 
• 2367-82-0 1,2,3,5-tetrafluorobenzene 

Relevant academic research and scientific papers

Homolytic Reactions of Polyfluoroaromatic Compounds. Part 16. Competitive Phenylation of Polyfluorobenzenes

Pairs of polyfluorobenzenes were allowed to compete for phenyl radicals generated by thermolysis of benzoyl peroxide at 80 deg C.From the relative yields of biaryl, and the yields of each biaryl formed upon arylation of each arene individually, the relative rates of attack of each site in each arene were deduced.Neither iron(III) benzoate nor trichloroacetic acid uniformly improved yields of biaryl, although in some cases the isomer distribution altered, when decomposition of benzoyl peroxide was carried out in the presence of such additives, to favour products of aryldehydrogenation or of aryldefluorination, respectively.Competition did not usually affect the distribution of attack of a particular arene, except when hexafluorobenzene was used, in which case greater selectivity of attack of the second arene occured.This suggested the formation of a 'stabilised' phenyl radical, and supported an earlier suggestion of species such as >; other evidence also supported the postulate.