23579-92-2

Basic information

• Product Name: 2-(METHOXYMETHYL)PYRIDINE
• Synonyms: Pyridine, 2-(methoxymethyl)-;2-(METHOXYMETHYL)PYRIDINE;METHYL (2-PICOLYL) ETHER;METHYL 2-PYRIDYLMETHYL ETHER;METHYL-2-METHYLPYRIDYL ETHER;2-(CH3OCH2)-pyridine;2-METHOXYMETHYL PYRIDINE 2-METHOXYMETHYL PYRIDINE;Nsc75841
• CAS NO: 23579-92-2
• Molecular Formula: C₇H₉NO
• Molecular Weight: 123.15
• Product Categories: Heterocycle-Pyridine series
• Mol File: 23579-92-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 158.549 °C at 760 mmHg
• Flash Point: 54.836 °C
• Appearance: /
• Density: 1.011 g/cm³
• Vapor Pressure: 3.38mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.34±0.12(Predicted)
• CAS DataBase Reference: 2-(METHOXYMETHYL)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHOXYMETHYL)PYRIDINE(23579-92-2)
• EPA Substance Registry System: 2-(METHOXYMETHYL)PYRIDINE(23579-92-2)

Safety Data

• Hazard Codes: Xi
• Statements: Xi:刺激性物质
• Hazardous Substances Data: 23579-92-2(Hazardous Substances Data)

Usage

General Description

2-(Methoxymethyl)pyridine is a chemical compound with the molecular formula C7H9NO. It is a pale yellow liquid with a strong, unpleasant odor. 2-(Methoxymethyl)pyridine is commonly used as an intermediate in the preparation of pharmaceuticals, agricultural chemicals, and organic compounds. It is also used as a solvent in various industrial applications. 2-(Methoxymethyl)pyridine is known to be a skin and eye irritant and should be handled with caution. It is important to follow proper safety protocols when working with this chemical.

InChI:InChI=1/C7H9NO/c1-9-6-7-4-2-3-5-8-7/h2-5H,6H2,1H3

Upstream product

• 4377-33-7 2-chloromethylpyridine 
• 124-41-4 sodium methylate 

Downstream Products

• 77823-45-1 1-methoxy-2-phenyl-indolizine 
• 88274-04-8 2-(4-Fluoro-phenyl)-1-methoxy-indolizine 
• 77823-47-3 (4-Hydroxy-phenyl)-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone 
• 77823-48-4 (3-Chloro-4-hydroxy-phenyl)-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone 
• 77823-46-2 1-methoxy-2-phenyl-3-(3-bromo-4-hydroxy-benzoyl)-indolizine 
• 77823-49-5 (4-Hydroxy-3-methoxy-phenyl)-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone 
• 88274-08-2 [2-(4-Fluoro-phenyl)-1-methoxy-indolizin-3-yl]-(4-hydroxy-3-methoxy-phenyl)-methanone 
• 79283-60-6 [4-(3-Dipropylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-62-8 [4-(3-Dibutylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-64-0 [3-Chloro-4-(3-dipropylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-68-4 [3-Bromo-4-(3-dipropylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-66-2 [3-Chloro-4-(3-dibutylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 79283-70-8 [3-Bromo-4-(3-dibutylamino-propoxy)-phenyl]-(1-methoxy-2-phenyl-indolizin-3-yl)-methanone; compound with oxalic acid 
• 353258-69-2 S-(4-chlorophenyl) pyridine-2-carbothioate 

Relevant articles and documents

Displacement of Pyridine-2-methanol from Dichloro(pyridine-2-methanolato)gold(III) in Acidic Solution. Ring Opening at Oxygen

The kinetics of displacement of pyridine-2-methanol (N-OH) from dichloro(pyridine-2-methanolato)gold(III), , have been studied in 5percent aqueous methanol at 25 deg C.In the presence of LiCl and perchloric acid the reaction consists of a pre-equilibrium protonation of the oxygen followed, first, by ring opening at oxygen accompanied by the entry of chloride or solvent, and then by displacement of the N-bonded pyridine-2-methanol to give -.This final stage is very similar to the displacement of 2-(methoxymethyl)pyridine (N-OMe) from .The ligand is not displaced in absence of chloride.The reaction between - and excess pyridine-2-methanol in 5percent methanol was also studied at 25 deg C.The initial attachement of the ligand by nitrogen is followed by rapid ring closing and a second molecule of ligand enters more slowly.The final product is + (isomeric form unknown), stabilised by the basic conditions generated by the excess ligand.Monodentate pyridine-2-methanol behaves as if it has a pKa of 5.6 with a steric hindrance comparable to that of 2-methylpyridine.