23592-79-2 Usage
Uses
Used in Pharmaceutical Industry:
Ethanone, 1-(4-methoxyphenyl)-2-[4-(phenylmethoxy)phenyl]is used as a building block for the synthesis of other compounds for various therapeutic purposes. Its unique structure and properties make it a valuable intermediate in organic synthesis, contributing to the development of medications with potential applications in drug discovery and development.
Used in Organic Synthesis:
In the field of organic synthesis, Ethanone, 1-(4-methoxyphenyl)-2-[4-(phenylmethoxy)phenyl]is utilized as a key intermediate for the creation of complex organic molecules. Its presence in the synthesis process allows for the formation of a wide range of compounds with diverse applications, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Drug Discovery and Development:
Ethanone, 1-(4-methoxyphenyl)-2-[4-(phenylmethoxy)phenyl]plays a crucial role in drug discovery and development, as its unique structure can be modified to create new compounds with potential therapeutic effects. Researchers can use Ethanone, 1-(4-methoxyphenyl)-2-[4-(phenylmethoxy)phenyl]- as a starting point to explore novel drug candidates, leading to the advancement of new treatments for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 23592-79-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,5,9 and 2 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 23592-79:
(7*2)+(6*3)+(5*5)+(4*9)+(3*2)+(2*7)+(1*9)=122
122 % 10 = 2
So 23592-79-2 is a valid CAS Registry Number.
23592-79-2Relevant academic research and scientific papers
Synthesis and Antiestrogenic Activity of Diaryl Thioether Derivatives
Poirier, Donald,Auger, Serge,Merand, Yves,Simard, Jacques,Labrie, Fernand
, p. 1115 - 1125 (2007/10/02)
The reaction of 1,2-diarylethanol and mercapto side chain catalyzed by ZnI2 was used as a key step in the short (three to five steps) and efficient synthesis of 17 diaryl thioether derivatives.Several of these compounds contain a methyl butyl amide chain and an hydroxyaryl moiety, respectively, for antiestrogenic activity and binding affinity on estrogen receptor.No binding affinity for crude cytosolic preparation of the estrogen receptor was observed for compounds without phenolic group, while a low affinity (0.01-0.05percent) was measured for mono- or diphenol derivatives.Like the pure steroidal antiestrogen EM-139, these novel nonsteroidal compounds did not exert any stimulatory effect on cell proliferation of (ER+) ZR-75-1 human breast cancer cells and partially reversed the amplitude of the stimulatory effect induced by estradiol on this (ER+) cell line.No proliferative or antiproliferative effect on (ER-) MDA-MB-231 human breast cancer cells was also observed for three of these compounds (39-41).Among the newly synthesized nonsteroidal compounds, the thioether derivative 41 (N-butyl-N-methyl-13,14-bis(4'-hydroxyphenyl)-12-thiatetradecanamide), with a long methylbutylalkanamide side chain and a diphenolic nucleus, was selected as the best antiestrogenic compound.However, this compound was 100-fold less antiestrogenic in (ER+) ZR-75-1 cells than the steroidal antiestrogen EM-139.
