23593-71-7 Usage
Uses
Used in Pharmaceutical Industry:
ClotriMazole IMpurity A is used as an impurity reference substance for the development and validation of analytical methods, ensuring the quality and safety of Clotrimazole-based antifungal medications. Its presence in the final product needs to be controlled and monitored to maintain the desired efficacy and minimize potential side effects.
Used in Research and Development:
ClotriMazole IMpurity A serves as a valuable compound in the study of the structure-activity relationship of Clotrimazole and its derivatives. Understanding the differences in biological activity between the isomers can provide insights into the design of more effective and targeted antifungal agents.
Used in Drug Metabolism and Pharmacokinetic Studies:
ClotriMazole IMpurity A is used as a research tool to investigate the metabolic pathways and pharmacokinetics of Clotrimazole in various biological systems. This information can be crucial for optimizing drug dosages and formulations, as well as predicting potential drug-drug interactions.
Used in Drug Safety Assessment:
ClotriMazole IMpurity A is utilized in safety assessment studies to evaluate the potential toxicological effects of the impurity. This helps in determining the acceptable levels of the impurity in the final drug product and ensuring patient safety during treatment.
Used in Drug Regulatory Compliance:
ClotriMazole IMpurity A is used to meet regulatory requirements for drug development, including the identification, qualification, and control of impurities in the manufacturing process. Compliance with these regulations is essential for obtaining marketing approval and ensuring the overall quality of the drug product.
Check Digit Verification of cas no
The CAS Registry Mumber 23593-71-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,5,9 and 3 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23593-71:
(7*2)+(6*3)+(5*5)+(4*9)+(3*3)+(2*7)+(1*1)=117
117 % 10 = 7
So 23593-71-7 is a valid CAS Registry Number.
23593-71-7Relevant academic research and scientific papers
Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
-
, (2008/06/13)
The present invention relates to chemical compounds having inhibitory activity on an intermediate conductance Ca 2+ activated potassium channel (IK Ca), and the use of such compounds for the treatment or alleviation of diseases or conditions relating to immune dysfunction. Moreover, the invention relates to a method of screening a chemical compound for inhibitory activity on an intermediate conductance Ca 2+ activated potassium channel (IK Ca).
Synthesis and antifungal activity of a series of difluorotritylimidazoles
Bartroli,Alguero,Boncompte,Forn
, p. 832 - 835 (2007/10/02)
1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole (flutrimazole, UR-4056, CAS 119006-77-8) (15) was selected among a series of mono-, di- and trifluorotrityl-imidazole antifungal agents as the most potent fluorine containing analogue of clotrimazole.
