236115-80-3Relevant academic research and scientific papers
Reexamination of neomycin B degradation: Efficient preparation of its CD and D rings as protected glycosyl donors
Wu, Baogen,Yang, Jun,He, Yun,Swayze, Eric E.
, p. 3455 - 3458 (2007/10/03)
(matrix presented) The degradation of neomycin B was reexamined, and a novel protocol was established to prepare the properly masked neomycin CD ring as a glycol donor in excellent yield. Glycosylation of the CD ring with glycol acceptors provided a facil
The chemistry of amine-azide interconversion: Catalytic diazotransfer and regioselective azide reduction
Nyffeler, Paul T.,Liang, Chang-Hsing,Koeller, Kathryn M.,Wong, Chi-Huey
, p. 10773 - 10778 (2007/10/03)
Azides have proven to be useful precursors to amines in organic syntheses. This report describes an improvement of the diazotransfer reaction and the first example of a regioselective azide reduction of compounds containing multiple azides. The use of a s
Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation
Greenberg, William A.,Priestley, E. Scott,Sears, Pamela S.,Alper, Phil B.,Rosenbohm, Christoph,Hendrix, Martin,Hung, Shang-Cheng,Wong, Chi-Huey
, p. 6527 - 6541 (2007/10/03)
The structure and activity of the pseudodisaccharide core found in aminoglycoside antibiotics was probed with a series of synthetic analogues in which the position of amino groups was varied around the glucopyranose ring. The naturally occurring structure
