2362008-83-9 Usage
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
(2-aminopyrimidin-5-yl)dimethylphosphine oxide serves as a key intermediate in the synthesis of a variety of pharmaceuticals and agrochemicals. Its unique properties allow it to be incorporated into the molecular structures of these compounds, potentially enhancing their efficacy and performance.
Used as a Ligand in Coordination Chemistry:
In the field of coordination chemistry, (2-aminopyrimidin-5-yl)dimethylphosphine oxide is utilized as a ligand. Its ability to form stable complexes with metal ions is valuable for the development of new materials and catalysts, which can have applications in various chemical processes and industrial applications.
Used in Medicinal Chemistry:
Due to its potential applications in medicinal chemistry, (2-aminopyrimidin-5-yl)dimethylphosphine oxide can be used in the development of new drugs. Its unique structure may contribute to the creation of pharmaceuticals with novel mechanisms of action or improved pharmacokinetic properties.
Used in Materials Chemistry:
In materials chemistry, (2-aminopyrimidin-5-yl)dimethylphosphine oxide may be employed in the design and synthesis of new materials with specific properties. Its incorporation into material structures could lead to advancements in areas such as polymer science, nanotechnology, and material coatings.
Check Digit Verification of cas no
The CAS Registry Mumber 2362008-83-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 2,3,6,2,0,0 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 2362008-83:
(9*2)+(8*3)+(7*6)+(6*2)+(5*0)+(4*0)+(3*8)+(2*8)+(1*3)=139
139 % 10 = 9
So 2362008-83-9 is a valid CAS Registry Number.
2362008-83-9Relevant academic research and scientific papers
Phosphine Oxides (-POMe2) for Medicinal Chemistry: Synthesis, Properties, and Applications
Stambirskyi, Maksym V.,Kostiuk, Tetiana,Sirobaba, Serhii I.,Rudnichenko, Alexander,Titikaiev, Dmytro L.,Dmytriv, Yurii V.,Kuznietsova, Halyna,Pishel, Iryna,Borysko, Petro,Mykhailiuk, Pavel K.
, p. 12783 - 12801 (2021/09/18)
A general practical approach to hetero(aromatic) and aliphatic P(O)Me2-substituted derivatives is elaborated. The key synthetic step was a [Pd]-mediated C-P coupling of (hetero)aryl bromides/iodides with HP(O)Me2. The P(O)Me2 substituent was shown to dramatically increase solubility and decrease lipophilicity of organic compounds. This tactic was used to improve the solubility of the antihypertensive drug prazosin without affecting its biological profile.
