23632-69-1

Basic information

• Product Name: benzyl (4S)-4-(2-tert-butoxy-2-oxo-ethyl)-5-oxo-oxazolidine-3-carboxylate
• CAS NO: 23632-69-1
• Molecular Formula: C₁₇H₂₁NO₆
• Molecular Weight: 335.35
• Mol File: 23632-69-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 488.1°C at 760 mmHg
• Flash Point: 249°C
• Density: 1.229g/cm³
• Vapor Pressure: 1.12E-09mmHg at 25°C
• Refractive Index: 1.529
• CAS DataBase Reference: benzyl (4S)-4-(2-tert-butoxy-2-oxo-ethyl)-5-oxo-oxazolidine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (4S)-4-(2-tert-butoxy-2-oxo-ethyl)-5-oxo-oxazolidine-3-carboxylate(23632-69-1)
• EPA Substance Registry System: benzyl (4S)-4-(2-tert-butoxy-2-oxo-ethyl)-5-oxo-oxazolidine-3-carboxylate(23632-69-1)

Safety Data

• Hazardous Substances Data: 23632-69-1(Hazardous Substances Data)

Upstream product

• 507-19-7 t-butyl bromide 
• 23632-66-8 (4S)-3-benzyloxycarbonyl-4-carboxymethyl-1,3-oxazolidin-5-one 
• 1152-61-0 N-Cbz-L-Asp 
• 24424-99-5 di-tert-butyl dicarbonate 
• 50-00-0 formaldehyd 
• 5545-52-8 Z-D(tBu)-OH 

Downstream Products

• 5545-52-8 Z-D(tBu)-OH 

Relevant articles and documents

Facile synthesis of tert-butyl ester of N-protected amino acids with tert-butyl bromide

A facile synthesis of a wide variety of N-benzyloxycarbonyl-amino acid-tert-butyl ester derivatives under mild conditions is described. N-protected amino acids were esterified with tert-butyl bromide in dimethylacetamide as solvent, in the presence of benzyltriethylammonium chloride (BTEAC)and a large excess of potassium carbonate. Many amino Z-acid-Tert-butyl esters that might be difficult to prepare by other methods have been synthesized in high yields by this procedure. The reaction is simple, unexpansive, easily scaled up, and proceeds without observable racemization.