236401-59-5Relevant academic research and scientific papers
Synthesis of the C(7)-C(20) fragment of spirotoamides A, B and C
Rossini, Allan F.C.,Dias, Luiz C.
, p. 1567 - 1578 (2019/10/01)
This work describes the preparation of the C(7)-C(20) fragment of spirotoamides A to C in a very elegant fashion, achievement very high levels of stereocontrol. The synthesis has been accomplished by a sequence involving 14 steps (0.36percent overall yiel
Polyoxygenated Tertiary Alcohols: A Kiyooka Approach
Lücke, Daniel,Kalesse, Markus
, p. 10080 - 10083 (2019/07/18)
A Kiyooka aldol approach for the stereoselective synthesis of tertiary alcohols is presented. This approach allows for the incorporation of different substituents at all three remaining positions at the chiral center bearing the tertiary alcohol. To demon
Chondramide C: Synthesis, configurational assignment, and structure-activity relationship studies
Eggert, Ulrike,Diestel, Randi,Sasse, Florenz,Jansen, Rolf,Kunze, Brigitte,Kalesse, Markus
supporting information; scheme or table, p. 6478 - 6482 (2009/03/11)
(Chemical Equation Presented) Two solutions for one problem: Of the four isomers of chondramide C synthesized, the two shown in the scheme exhibit nearly the same conformation of the peptide segment and consequently unfold equal biological activities.
Total synthesis of elaiolide using a copper(l)-promoted stille cyclodimerization reaction
Paterson, Ian,Lombart, Henry-Georges,Allerton, Charlotte
, p. 19 - 22 (2008/02/09)
(equation presented) Elaiolide (2) The 16-membered macrodiolide elaiolide (2) has been prepared in 20 steps from the ketone (S)-8 in 9.3% overall yield with a diastereoselectivity of 76%. Key steps included the copper(l) thiophene-2-carboxylate promoted c
