1428737-98-7Relevant articles and documents
Synthesis of the C(7)-C(20) fragment of spirotoamides A, B and C
Rossini, Allan F.C.,Dias, Luiz C.
, p. 1567 - 1578 (2019/10/01)
This work describes the preparation of the C(7)-C(20) fragment of spirotoamides A to C in a very elegant fashion, achievement very high levels of stereocontrol. The synthesis has been accomplished by a sequence involving 14 steps (0.36percent overall yiel
Synthesis of the C-1-C-17 fragment of amphidinolides C, C2, C3, and F
Clark, J. Stephen,Yang, Guang,Osnowski, Andrew P.
, p. 1460 - 1463 (2013/06/26)
The C-1-C-17 fragment of amphidinolides C, C2, C3, and F has been constructed from a trans-2,5-disubstituted dihydrofuranone prepared by diastereoselective rearrangement of a free or metal-bound oxonium ylide generated from a metal carbenoid. The dihydrofuranone was converted into an aldehyde corresponding to the C-1-C-8 framework, and this was coupled to the C-9-C-17 unit by nucleophilic addition of a vinylic anion.