236408-20-1

Basic information

• Product Name: (1S)-(2,5-DIMETHOXY-2,5-DIHYDROFURAN-2-YL)ETHANOL
• Synonyms: (1S)-1-(2,5-Dimethoxy-2,5-dihydrofuran-2-yl)ethanol;(1S)-(2,5-DIMETHOXY-2,5-DIHYDROFURAN-2-YL)ETHANOL;(1s)-2,5-dihydro-2,5-dimethoxy-alpha-methyl-2-furanmethanol;(1S)-1-(2,5-DIMETHOXY-2,5-DIHYDROFURAN-2- YL)ETHANOL 98%;(1S)-1-(2,5-Dimethoxy-2,5-dihydrofuran-2-yl)ethanol,98%
• CAS NO: 236408-20-1
• Molecular Formula: C8H14O4
• Molecular Weight: 174.19
• Mol File: 236408-20-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 72-76 °C (1.5 mmHg)
• Flash Point: 111.6 °C
• Appearance: /
• Density: 1.1699 (rough estimate)
• Vapor Pressure: 0.00171mmHg at 25°C
• Refractive Index: 1.4455 (estimate)
• Storage Temp.: Refrigerator (+4°C)
• PKA: 14.34±0.20(Predicted)
• CAS DataBase Reference: (1S)-(2,5-DIMETHOXY-2,5-DIHYDROFURAN-2-YL)ETHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (1S)-(2,5-DIMETHOXY-2,5-DIHYDROFURAN-2-YL)ETHANOL(236408-20-1)
• EPA Substance Registry System: (1S)-(2,5-DIMETHOXY-2,5-DIHYDROFURAN-2-YL)ETHANOL(236408-20-1)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 236408-20-1(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow viscous liquid

InChI:InChI=1/C8H14O4/c1-6(9)8(11-3)5-4-7(10-2)12-8/h4-7,9H,1-3H3/t6-,7-,8+/m0/s1

Upstream product

• 113531-28-5 Octanoic acid 1-furan-2-yl-ethyl ester 
• 4208-64-4 1-(2-furyl)ethanol 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 67-56-1 methanol 
• 4208-64-4 (S)-1-(2-furanyl)ethanol 
• 13129-26-5 1-(3'-furyl)-ethanol 

Relevant articles and documents

Electroorganic synthesis on the solid phase using polymer beads as supports

Chemistry with currents: The application of an indirect electroorganic approach has enabled electroorganic reactions on solid phases to be performed for the first time using commercially available polystyrene beads (see picture, Med = redox catalyst). The 2,5-dimethoxylation of a variety of furans was undertaken. This strategy can be integrated into multistep solid-phase synthesis.

Development of a novel environmentally friendly electrolytic system by using recyclable solid-supported bases for in situ generation of a supporting electrolyte from methanol as a solvent: Application for Anodic methoxylation of organic compounds

We have successfully developed a novel environmentally friendly electrolytic system using recyclable solid-supported bases for in situ generation of a supporting electrolyte from methanol as a solvent. It was found that solid-supported bases are electrochemically inactive at an electrode surface. It was also found that solid-supported bases dissociate methanol into methoxide anions and protons. Therefore, in the presence of solid-supported bases, it was clarified that methanol serves as both a solvent and a supporting electrolyte generated in situ. Anodic methoxylation of various compounds with solid-supported bases was carried out to provide the corresponding methoxylated products in good to excellent yields with a few exceptions. The methoxylated products and the solid-supported bases were easily separated by only filtration, and the desired pure methoxylated products were readily isolated simply by concentration of the filtrates. The separated and recovered solid-supported bases were recyclable for several times.

Synthesis of 1-(2,5-dimethoxy-2,5-dihydrofuran-2-yl)ethanol from 2-acetylfuran

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