236742-98-6

Basic information

• Product Name: (4S)-3-oxo-4,5-(N-triphenylmethylepimino)pentanoic acid isopropyl ester
• Synonyms: (4S)-3-oxo-4,5-(N-triphenylmethylepimino)pentanoic acid isopropyl ester
• CAS NO: 236742-98-6
• Molecular Weight: 413.516
• Mol File: 236742-98-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-3-oxo-4,5-(N-triphenylmethylepimino)pentanoic acid isopropyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-3-oxo-4,5-(N-triphenylmethylepimino)pentanoic acid isopropyl ester(236742-98-6)
• EPA Substance Registry System: (4S)-3-oxo-4,5-(N-triphenylmethylepimino)pentanoic acid isopropyl ester(236742-98-6)

Safety Data

• Hazardous Substances Data: 236742-98-6(Hazardous Substances Data)

Upstream product

• 108-21-4 Isopropyl acetate 
• 75154-68-6 methyl (2S)-N-tritylaziridine-2-carboxylate 

Downstream Products

• 236742-79-3 (1'R)-E-5-trimethylsilyl-3-(N-triphenylmethylaziridinyl)-2-penten-4-ynoic acid isopropyl ester 

Relevant articles and documents

Synthesis of optically active N-allyl amino compounds with defined trisubstituted double bonds

Optically active acyclic N-allylamino compounds with defined configurated trisubstituted double bonds were generated via a three step sequence. The first crucial step was a two-carbon chain elongation of chiral α-aminoacid esters succeeding in a Claisen ester condensation with acetic acid ester enolates. The so formed β-ketoesters were subjected to a one pot procedure of an enol trifluoromethanesulfonate generation and a consecutive palladium catalysed cross-coupling: A Stille or a Sonogashira type reaction allowed to generate selectively the trisubstituted E-olefins.