236743-98-9 Usage
General Description
Trabectedin intermediate is a chemical component used in the manufacturing process of Trabectedin, a chemotherapy drug primarily used to treat advanced-stage soft tissue sarcoma. This intermediate ingredient plays a crucial role in the final formulation, as it holds therapeutic properties in fighting cancer. Trabectedin intermediate is known for its cytotoxic nature that aids in interfering with the DNA repair mechanism in cancer cells. It is pivotal in the pharmaceutical industry due to its efficacy in cancer treatment. However, the precise chemical constituents and properties of the Trabectedin intermediate can vary depending on the preparation process and methodology.
Check Digit Verification of cas no
The CAS Registry Mumber 236743-98-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,6,7,4 and 3 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 236743-98:
(8*2)+(7*3)+(6*6)+(5*7)+(4*4)+(3*3)+(2*9)+(1*8)=159
159 % 10 = 9
So 236743-98-9 is a valid CAS Registry Number.
236743-98-9Relevant articles and documents
Synthesis of ecteinascidin ET-743 and phthalascidin Pt-650 from cyanosafracin B
Cuevas, Carmen,Perez, Marta,Martin, Maria J.,Chicharro, Jose L.,Fernandez-Rivas, Carolina,Flores, Maria,Francesch, Andres,Gallego, Pilar,Zarzuelo, Maria,De La Calle, Fernando,Garcia, Jesus,Polanco, Concepcion,Rodriguez, Ignacio,Manzanares, Ignacio
, p. 2545 - 2548 (2007/10/03)
(equation presented) An efficient new process is described for the synthesis of ecteinascidin ET-743 (1) and phthalascidin (2), starting from readily available cyanosafracin B (3).
