23690-13-3

Basic information

• Product Name: 1-(2,4-dimethoxyphenyl)propan-2-amine
• Synonyms: α-Methyl-2,4-dimethoxyphenethylamine;1-(2,4-dimethoxyphenyl)propan-2-amine;1-(2,4-Dimethoxyphenyl)-2-propanamine;1-Methyl-2-(2,4-dimethoxyphenyl)ethanamine;2,4-Dimethoxyamphetamine;α-Methyl-2,4-dimethoxybenzeneethanamine
• CAS NO: 23690-13-3
• Molecular Formula: C₁₁H₁₇NO₂
• Molecular Weight: 195.2582
• Mol File: 23690-13-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 295.7°Cat760mmHg
• Flash Point: 144.4°C
• Appearance: /
• Density: 1.023g/cm³
• Vapor Pressure: 0.0015mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: 1-(2,4-dimethoxyphenyl)propan-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-dimethoxyphenyl)propan-2-amine(23690-13-3)
• EPA Substance Registry System: 1-(2,4-dimethoxyphenyl)propan-2-amine(23690-13-3)

Safety Data

• Hazardous Substances Data: 23690-13-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H17NO2/c1-8(12)6-9-4-5-10(13-2)7-11(9)14-3/h4-5,7-8H,6,12H2,1-3H3

Upstream product

• 15804-78-1 1-(2,4-Dimethoxyphenyl)-2-nitropropen 
• 831-29-8 1-(2,4-dimethoxyphenyl)propan-2-one 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 1161921-17-0 [2-(2,4-dimethoxyphenyl)-1-methylethylamino]acetonitrile 
• 60917-67-1 5-bromo-2,4-dimethoxyamphetamine 

Relevant articles and documents

Synthesis and characterization of hydroxylated mesocarb metabolites for doping control

The synthesis and method of analysis of hydroxylated mesocarb metabolites are described. Six potential hydroxylated mesocarb metabolites were prepared, characterized, and compared with the mesocarb metabolites synthesized enzymatically in vitro using human liver proteins and also compared with metabolites extracted from human urine after oral administration of mesocarb. p-Hydroxymesocarb was the most prevalent metabolite (conjugated and non-conjugated) observed. With respect to doping analysis, synthesis of p-hydroxymesocarb, the main urinary metabolite of mesocarb, and its availability as a reference material is important.

Binding of Phenylalkylamine Derivatives at 5-HT1C and 5-HT2 Serotonin Receptors: Evidence for a Lack of Selectivity

Certain phenyalkylamine derivatives have been considered to bind selectively at 5-HT2 serotonin receptors.It is now recognized that the most widely used derivatives, i.e., 1-(2,5-dimethoxy-4-X-phenyl)-2-aminopropanes where X = Me (DOM), Br (DOB), and I (DOI) (1-3, respectively) also bind at the more recently identified population of serotonin 5-HT1C receptors.The purpose of the present investigation was to determine whether simple phenylalkylamines bind selectively at one population of receptors over the other.An examination of 34 derivatives reveals (i) similar structure-affinity relationships and (ii) a significant correlation (r = >0.9, n = 25) between 5-HT1C and 5-HT2 affinity.None of the compounds included in the present study displayed more than a 10-fold selectivity for one population of these receptors over the other; the results suggest that these compounds (including the widely used 5-HT2 agonists DOB and DOI) are 5-HT1C/5-HT2 agents.