15804-78-1

Basic information

• Product Name: 1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE
• Synonyms: 1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE, >95%;2,4-dimethoxy-1-(2-nitro-1-propen-1-yl)benzene
• CAS NO: 15804-78-1
• Molecular Formula: C₁₁H₁₃NO₄
• Molecular Weight: 223.23
• Mol File: 15804-78-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 364.6°Cat760mmHg
• Flash Point: 163.6°C
• Appearance: /
• Density: 1.168g/cm³
• Vapor Pressure: 3.5E-05mmHg at 25°C
• Refractive Index: 1.555
• CAS DataBase Reference: 1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE(15804-78-1)
• EPA Substance Registry System: 1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE(15804-78-1)

Safety Data

• Hazardous Substances Data: 15804-78-1(Hazardous Substances Data)

Usage

General Description

1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE is a chemical compound with the molecular formula C11H13NO4. It is a nitroalkene derivative of 2,4-DIMETHOXYPHENYL, and is commonly used in organic synthesis as a precursor for the preparation of various pharmaceuticals and other chemical products. 1-(2,4-DIMETHOXYPHENYL)-2-NITROPROPENE is an important intermediate in the production of a variety of organic compounds and is known for its use in the synthesis of various bioactive molecules. It is a yellow liquid at room temperature and is known to be highly reactive, making it an important reagent in the field of organic chemistry.

InChI:InChI=1/C11H13NO4/c1-8(12(13)14)6-9-4-5-10(15-2)7-11(9)16-3/h4-7H,1-3H3/b8-6+

Upstream product

• 79-24-3 Nitroethane 
• 75-04-7 ethylamine 
• 613-45-6 2,4-Dimethoxybenzaldehyde 

Downstream Products

• 91474-01-0 5-<(Acetyl)(tert-butoxycarbonyl)methylenamino>-4-(2,4-dimethoxyphenyl)-4,5-dihydro-2,5-dimethyl-3-furancarbonsaeure-tert-butylester 
• 1014-24-0 1-(2,4-dimethoxyphenyl)propan-2-ol 
• 98450-74-9 4-(2,4-Dimethoxyphenyl)-1-<2-methoxy-1-(methoxycarbonyl)-1-propenyl>-2,5-dimethyl-3-pyrrolcarbonsaeure-methylester 
• 98450-46-5 4-(2,4-Dimethoxyphenyl)-1-<2-hydroxy-1-(methoxycarbonyl)-1-propenyl>-2,5-dimethyl-3-pyrrolcarbonsaeure-methylester 
• 23690-13-3 2,4-dimethoxyamphetamine 
• 831-29-8 1-(2,4-dimethoxyphenyl)propan-2-one 

Relevant articles and documents

Binding of Phenylalkylamine Derivatives at 5-HT1C and 5-HT2 Serotonin Receptors: Evidence for a Lack of Selectivity

Certain phenyalkylamine derivatives have been considered to bind selectively at 5-HT2 serotonin receptors.It is now recognized that the most widely used derivatives, i.e., 1-(2,5-dimethoxy-4-X-phenyl)-2-aminopropanes where X = Me (DOM), Br (DOB), and I (DOI) (1-3, respectively) also bind at the more recently identified population of serotonin 5-HT1C receptors.The purpose of the present investigation was to determine whether simple phenylalkylamines bind selectively at one population of receptors over the other.An examination of 34 derivatives reveals (i) similar structure-affinity relationships and (ii) a significant correlation (r = >0.9, n = 25) between 5-HT1C and 5-HT2 affinity.None of the compounds included in the present study displayed more than a 10-fold selectivity for one population of these receptors over the other; the results suggest that these compounds (including the widely used 5-HT2 agonists DOB and DOI) are 5-HT1C/5-HT2 agents.

A Simple Unusual One-Step Conversion of Aromatic Aldehydes into Nitriles

-