23708-08-9

Upstream product

• 18483-64-2 mammeisin 
• 883-75-0 3,4-Dihydro-5-hydroxy-7-methoxy-2,2-dimethyl-2H-1-benzopyran 
• 94-02-0 ethyl 3-oxo-3-phenylpropionate 

Downstream Products

• 908601-12-7 8,8-dimethyl-5-(2-oxopropoxy)-4-phenyl-9,10-dihydropyrano[2,3-f]chromen-2-one 
• 908601-11-6 8,8-dimethyl-5-propionyloxy-4-phenyl-9,10-dihydropyrano[2,3-f]chromen-2-one 
• 64620-10-6 5-methoxy-8,8-dimethyl-4-phenyl-9,10-dihydropyrano[2,3-f]chromen-2-one 
• 53981-41-2 5-acetoxy-8,8-dimethyl-4-phenyl-9,10-dihydropyrano[2,3-f]chromen-2-one 

Relevant academic research and scientific papers

Modified coumarins. 21. Synthesis of neoflavones produced by Marila pluricostata and their derivatives

Natural neoflavones 5-hydroxy-8,8-dimethyl-4-phenyl-9,10-dihydropyrano[2,3- f]chromen-2-one and 5-hydroxy-8,8-dimethyl-6-propionyl-4-phenyl-9,10- dihydropyrano[2,3-f]chromen-2-one and their derivatives were synthesized. 2006 Springer Science+Business Medi

Cytotoxic 4-phenylcoumarins from the leaves of Marila pluricostata

Bioassay-guided fractionation of the CH2Cl2 extract of the leaves of Marila pluricostata led to the isolation of 17 naturally occurring 4-phenylcoumarins, three of them, 5-hydroxy-8,8-dimethyl-4-phenyl-9, 10-dihydro-8H-pyrano-[2,3-f]chromen-2-one(1),5-hydroxy-8,8-dimethyl-4-phenyl-6- propionyl-9,10-dihydro-8H-pyrano-[2,3-f]chromen-2-one (2), and 5,7-dihydroxy-8-(3-methylbut-2-enyl)-4-phenylchromen-2-one (3), are new natural compounds; the remaining (4-17) are known mammea-type coumarins. Their structures were established by spectroscopic means. All compounds were tested in cytotoxicity assays against the MCF-7, II-460, and SF-268 human cancer cell lines.