2371-25-7

Basic information

• Product Name: ethyl [(2,6-dimethylphenyl)amino]acetate
• Synonyms: ethyl [(2,6-dimethylphenyl)amino]acetate
• CAS NO: 2371-25-7
• Molecular Weight: 207.272
• Mol File: 2371-25-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: ethyl [(2,6-dimethylphenyl)amino]acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl [(2,6-dimethylphenyl)amino]acetate(2371-25-7)
• EPA Substance Registry System: ethyl [(2,6-dimethylphenyl)amino]acetate(2371-25-7)

Safety Data

• Hazardous Substances Data: 2371-25-7(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 87-62-7 2,6-dimethylaniline 
• 105-36-2 ethyl bromoacetate 
• 105-39-5 chloroacetic acid ethyl ester 

Downstream Products

• 103095-36-9 2,6-dimethylanilino-acetic acid 
• 2370-48-1 2-[(2,6-dimethylphenyl)amino]acetohydrazide 
• 71455-98-6 ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]-4-(2,6-dimethylanilino)butyrate 
• 71456-30-9 N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]-4-(2,6-dimethylanilino)butyric acid 
• 71456-22-9 ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]aminopropionate 
• 71456-21-8 ethyl N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]glycinate 
• 71455-86-2 N-[N-(p-chlorobenzoyl)-2-(2,6-dimethylanilino)acetyl]glycine 
• 104411-97-4 3-(2,6-dimethylphenyl)sydnone 
• 104412-24-0 C₁₀H₁₂N₂O₃ 
• 87544-47-6 3-(2,6-Dimethyl-phenyl)-5-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylic acid ethyl ester 
• 87544-48-7 N-[3-(2,6-Dimethyl-phenyl)-5-oxo-thiazolidin-(2Z)-ylidene]-4-methoxy-benzamide 
• 87544-39-6 3-(2,6-Dimethyl-phenyl)-5-phenyl-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylic acid ethyl ester 
• 87544-46-5 3-(2,6-Dimethyl-phenyl)-5-(4-methoxy-phenyl)-2-thioxo-2,3-dihydro-1H-imidazole-4-carboxylic acid 

Relevant articles and documents

Synthesis, cytotoxic evaluation, and molecular docking studies of new oxadiazole analogues

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A series of 1-(substituted phenyl)-3-[α-(alkyloxyimino)-benzylidene] pyrrolidine-2,4-dione derivatives as a mixture of two geometrical isomers of Z-configuration and E-configu-ration were synthesized by the reaction of the corresponding α -hydroxybenzylidene analogs with alkyloxyamine hydro-chlorides. The target compounds were confirmed by IR, 1 H NMR, MS and elemental analysis. The title compounds exhibit inhibitory activity against Echinochloa crusgalli and Brassica campestris. Copyright by Walter de Gruyter Berlin Boston.

Angiotensin converting enzyme inhibitors: N-substituted monocyclic and bicyclic amino acid derivatives

The synthesis of N-(3-mercaptopropionyl)-N-arylglycines (14a-x), -N-arylalanines (15a,b), -N-cycloalkylglycines (16a-k), and -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids (17a-d), -1,2,3,4-tetrahydroquinoline-2-carboxylic acids (18a-f), and -indoline-2-carboxylic acids (19a-k) is described. In vitro inhibition of angiotensin converting enzyme (ACE) is reported for each compound, and the structure-activity relationship for each series is discussed. The in vivo inhibition of ACE and antihypertensive effects of representative compounds from each series are discussed. The most potent compound, 19d, had an in vitro ACE IC50 of 2.6 x 10-9 M and lowered blood pressure in spontaneous hypertensive rats 85 mm at a dose of 10 mg/kg po.