23717-59-1

Usage

Appearance

Yellow to orange crystalline solid The compound is a yellow to orange solid with a crystalline structure.

Solubility

Insoluble in water, soluble in organic solvents The compound does not dissolve in water but can dissolve in certain organic solvents, such as ethanol or acetone.

Uses

Dye, pharmaceutical synthesis, chemical intermediate 2,2-diphenyl-1H-indene-1,3(2H)-dione is used in the production of dyes, as a starting material for synthesizing pharmaceuticals, and as a chemical intermediate in various chemical reactions.

Reagent in organic chemistry

The compound serves as a reagent in organic chemistry reactions, aiding in the synthesis of other compounds or the study of reaction mechanisms.

Biological and pharmacological properties

The compound has been studied for its potential anti-inflammatory and anti-cancer properties, indicating possible applications in the medical field.

Wide range of applications

Due to its various uses and potential properties, 2,2-diphenyl-1H-indene-1,3(2H)-dione has a broad range of applications across different fields, including chemistry, pharmaceuticals, and medicine.

Upstream product

• 938-24-9 indantrione 
• 71-43-2 benzene 
• 485-47-2 indan-1,2,3-trione hydrate 
• 83-12-5 phenindione 
• 14190-17-1 diphenyliodonium acetate 
• 105639-57-4 [(trimethylsilyl)ethynyl]phenyliodonium triflate 
• 144930-55-2 (4-iodophenyl)(phenyl)iodonium trifluoromethanesulfonate 
• 61260-15-9 dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate 
• 1801-25-8 3-(diphenylmethylene)isobenzofuran-1(3H)-one 
• 119-61-9 benzophenone 
• 536-80-1 iodosylbenzene 
• 1483-72-3 diphenyliodonium chloride 
• 91446-49-0 sodium 2-(ethoxycarbonyl)-1-oxo-1H-inden-3-olate 
• 606-23-5 1H-indene-1,3(2H)-dione 

Downstream Products

• 40650-79-1 3-Benzhydrylidene-1,1-diphenyl-1,3-dihydro-isobenzofuran 
• 22253-09-4 2,2-Diphenyl-indan 
• 71824-24-3 2-(2-aminoethyl)-1H-isoindole-1,3(2H)-dione 
• 101-81-5 Diphenylmethane 
• 1801-25-8 3-(diphenylmethylene)isobenzofuran-1(3H)-one 

Relevant academic research and scientific papers

A study on the reaction of 3-Alkyl(aryl)imidazo[1,5-A]pyridines with ninhydrin

The reaction of 3-Alkyl(aryl)imidazo[1,5-A]pyridines (1) with ninhydrin in dichloromethane at room temperature delivered good yields of the respective 2-hydroxy-2-(imidazo[1,5-A]pyridine-1-yl)indene-1,3-diones. In the presence of dimethyl acetylenedicarbo

A new, efficient method for direct α-alkenylation of β-dicarbonyl compounds and phenols using alkenyltriarylbismuthonium salts

Direct α-alkenylation of β-keto esters, β-diketone, and phenols with alkenyltriarylbismuthonium salts proceeded smoothly in the presence of 1,1,3,3-tetramethylguanidine to afford the corresponding α-alkenylated carbonyl compounds (β,γ-unsaturated carbonyl compounds) in good yields. The high leaving ability of the triarylbismuthonio group is a key driving force to achieve the C-C bond formation at the vinylic carbon under mild conditions.

Acid-Catalyzed Condensations of Ninhydrin with Aromatic Compounds. Preparation of 2,2-Diaryl-1,3-indanediones and 3-(Diarylmethylene)isobenzofuranones 1

Ninhydrin (1) reacts with aromatic compounds in acid solution to give condensation products. In H2SO4, 1 reacts with arenes to give 2,2-diaryl-1,3-indanediones (2a-f). In superacidic triflic acid (CF3SO3H, TfOH)

A study on the friedel-crafts type reaction of ninhydrin with arenes

The reactions of ninhydrin (1, 1,2,3-indantrione) with arenes in the presence of concentrated sulfuric acid afforded mono- or di-substituted ninhydrin derivatives at the 2-position in reasonable yields.

α-Vinylation of 1,3-Dicarbonyl Compounds with Alkenyl(aryl)iodonium Tetrafluoroborates: Effects of Substituents on the Aromatic Ring and of Radical Inhibitors

Direct α-vinylations of enolate anions derived from 1,3-dicarbonyl compounds with 4-teri-butyl-1- cyclohexenyl(aryl)iodonium 2 and 1-cyclopentenyl(aryl)iodonium tetrafluoroborates 3 are reported. Frequently, α-phenylations compete with the vinylations in the reaction of 1,3-dicarbonyl compounds with alkenyl(phenyl)iodonium salts 2a and 3a. Use of alkenyl(p-methoxyphenyl)iodonium salts 2b and 3b, however, leads to selective α-vinylation at the expense of the competing arylation of 1,3-dicarbonyl compounds. Use of an efficient aryl radical trap, 1,1-diphenylethylene, inhibits radical-induced decomposition of the alkenyl(aryl)iodonium salts, thereby improving the yields of α-vinylations of enolate anions derived from 1,3-dicarbonyl compounds.

Reaction of alkynyl(phenyl)(p-phenylene)bisiodonium ditriflates with nucleophiles. High reactivity of the alkynyl component

Reaction of alkynyl (p-phenylene) bisiodonium ditriflates with potassium thiocyanate in DMF gave alkynyl thiocyanates and p-iodophenyl (phenyl) iodonium triflate. The latter was readily removed by washing with water. The exclusive sulfur attack of thiocya

Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with ketones: Synthesis of 3-ylidenephthalides and their conversion to 2,2-disubstituted indan-1,3-diones including spirocyclic compounds

The Wittig-Horner reaction of dimethyl phthalide-3-phosphonates with various ketones was investigated under the conditions: lithium bis(trimethylsilyl)amide (LHMDS) or sodium hydride in tetrahydrofuran, and cesium carbonate in isopropyl alcohol. The sequential treatment of the 3-ylidenephthalides with diisobutylaluminium hydride (DIBAL-H) and pyridinium dichromate (PDC) afforded 2,2-disubstituted indan-1,3-dione derivatives in modest to high overall yields.