71824-24-3Relevant articles and documents
COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG, AT LEAST ONE IONIC SPECIES AND AN AMPHOIPHILIC COMPOUNDS CONTAINING HYDRIPHOBIC RADICALS
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, (2021/08/13)
A composition in the form of an injectable solution includes: amylin, an amylin receptor agonist or an amylin analog; at least one ionic species; and an amphiphilic compound having a hydrophilic skeleton HB, substituted by at least one hydrophobic radical -Hy according to formula (I). A composition further is characterised in that it also has prandial insulin. In one embodiment, the composition also has GLP-1, GLP-1 analogs, and GLP-1 receptor agonists, commonly called GLP-1 RA.
Asymmetric aluminum complex containing acetylacetone derivative as well as preparation method and application thereof
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Paragraph 0033, (2018/05/16)
The invention discloses an asymmetric aluminum complex containing an acetylacetone derivative as well as a preparation method and application thereof. The asymmetric aluminum complex has a structuralformula shown as a formula I, wherein R1 is trifluoromethyl or methyl and R2 is phenyl, trifluoromethyl or methyl. The asymmetric aluminum complex catalyst containing the acetylacetone derivative disclosed by the invention is prepared from a ligand and trimethyl aluminum through reaction and has the advantages of simple preparation method, low cost and high product yield; the complex has a specialstructure and metal central aluminum is coordinated with divalent N, N, O and O of the ligand; the complex can be used as a catalyst for cyclic lactone ring-opening polymerization reaction and has the advantages of high catalytic activity, good stereoselectivity and rapid reaction speed; the polymerization reaction is simple to operate and an obtained polymerized product has narrow molecular weight distribution, controllable molecular weight and high yield; the asymmetric aluminum complex can be widely used for cyclic lactone ring-opening polymerization and is a very ideal catalyst. (The formula I is shown in the description.).
Aluminum complexes containing salicylic aldehyde group as well as preparation method and application of complexes
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Paragraph 0033, (2018/07/30)
The invention discloses aluminum complexes containing a salicylic aldehyde group as well as a preparation method and application of the complexes. The complexes have a structural formula shown in a formula I in the description, wherein R is hydrogen, a C1-C4 alkane or a halogen. The aluminum complex catalyst containing the salicylic aldehyde group provided by the invention is obtained by reactinga ligand with trimethylaluminum, the preparation method is simple, the costs are low, and the product yield is high; the compounds have a special structure, the structure is various, and metal centralaluminum and divalent N, N, O and O of the ligand are subjected to coordination; the complexes can be used as a catalyst for a ring-opening polymerization reaction of a cyclic lactone and has high catalytic activity, good stereoselectivity and a high reaction speed, and the polymerization reaction is simple to operate; and the obtained polymer product has narrow molecular weight distribution, a controllable molecular weight and a high yield, can be widely used in ring-opening polymerization of the cyclic lactone, and is an ideal catalyst.