23724-60-9

Basic information

• Product Name: ACETAMIDE-2,2,2-D3
• Synonyms: ACETAMIDE-2,2,2-D3;ACETAMIDE-2 2 2-D3 99 ATOM % D
• CAS NO: 23724-60-9
• Molecular Formula: C₂H₅NO
• Molecular Weight: 62.09
• EINECS: 200-473-5
• Mol File: 23724-60-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 78-80 °C(lit.)
• Boiling Point: 221 °C(lit.)
• Appearance: /
• Storage Temp.: Room Temperature
• Solubility: DMSO (Soluble), Methanol (Slightly)
• CAS DataBase Reference: ACETAMIDE-2,2,2-D3(CAS DataBase Reference)
• NIST Chemistry Reference: ACETAMIDE-2,2,2-D3(23724-60-9)
• EPA Substance Registry System: ACETAMIDE-2,2,2-D3(23724-60-9)

Safety Data

• Hazard Codes: Xn
• Statements: 40
• Safety Statements: 36/37
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 1
• Hazardous Substances Data: 23724-60-9(Hazardous Substances Data)

Usage

Uses

Acetamide-2,2,2-d3 is used in infrared spectral studies and normal vibrations of acetamide and it’s deutrated analogs.

Upstream product

• 1186-52-3 tetradeuterioacetic acid 
• 53778-70-4 trideuteroacetic acid isopropyl ester 
• 1112-02-3 d⁽³⁾-acetic acid 
• 2206-26-0 [D₃]acetonitrile 

Downstream Products

• 16727-10-9 Perdeutero-N,N-dimethyl-acetamid 
• 114533-13-0 N-benzyl-[C-²H₃]acetamide 

Relevant articles and documents

A low temperature matrix isolation infrared study of acetamides. I. Acetamide and some deuterated derivatives

The IR spectra of acetamide and some of its deuterated derivatives in argon matrices (14 K) have been obtained in the region 4000-200 cm-1.An injection system was developed to avoid multiple site splitting.A normal coordinate analysis has been carried out for the a" vibrational modes and from the C NH2 torsional force constant the potential barrier was calculated to be 81 kJ mol-1.

DEUTERATED FEZOLINETANT

The present invention relates to deuterated fezolinetant (R)-(4-fluorophenyl)-(8-methyl-3-(3-(methyl-d3)-1,2,4-thiadiazol-5-yl)-5,6-dihydro-[1,2,4]trizolo[4,3-a]pyrazin-7(8H)-yl)methanone, or a pharmaceutically acceptable solvate thereof, as NK-3 antagoni

Transamidation of primary amides with amines catalyzed by zirconocene dichloride

Zirconocene dichloride (Cp2ZrCl2) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80°C in 5-24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30°C.