1186-52-3

Usage

Uses

1. Used in NMR Spectroscopy:
ACETIC-D3 ACID-D is used as an NMR solvent for the analysis and profiling of biological samples resolved through NMR spectroscopy. It is particularly useful for labeling RNA for high-resolution NMR.
2. Used in Food Industry:
ACETIC-D3 ACID-D serves as a deuterated, polar, and protic solvent in the food industry. It is used as a preservative, pH control agent, and flavor enhancer, contributing to the quality and shelf life of various food products.
3. Used in Chemical Synthesis:
ACETIC-D3 ACID-D may be used in the synthesis of deuterated compounds, such as (7E,9Z)-CLA (conjugated linoleic acid) and Pr(CD3COO)3.D2O (deuterium analog of praseodymium (III) acetate hydrate). These synthesized compounds have potential applications in various fields, including pharmaceuticals and materials science.

InChI:InChI=1/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/i1D3/hD

Upstream product

• 114379-93-0 benzyl <2-²H3>ethanoate 
• 504-64-3 carbon suboxide 
• 7789-20-0 water-d2 
• 16873-17-9 deuterium 
• 813-56-9 tetradeuterio-malonic acid 
• 141-82-2 malonic acid 
• 14044-94-1 sodium trideuterioacetate 
• 7698-05-7 hydrogen chloride 
• 36810-80-7 C₁₀H₈⁽²⁾H₅NO 
• 76-05-1 trifluoroacetic acid 

Downstream Products

• 1112-02-3 d⁽³⁾-acetic acid 
• 486-25-9 9-fluorenone 
• 117121-81-0 deuterated ethyl acetate 
• 90691-33-1 ethyl <2H3>acetate 
• 536-50-5 CH₃C₆H₄CH(CH₃)OH 
• 86561-30-0 1-(4-methylphenyl)ethyl acetate 
• 5437-59-2 1-(4-methylphenyl)-1-nitroethane 
• 62559-41-5 4-ethyl-3-nitrotoluene 
• 34681-89-5 2-ethyl-5-methylphenyl acetate 
• 113386-51-9 bis-p-methoxyphenyl-trans-1,1'-bi(1,2-dihydrophthalazinylidene) 
• 622-25-3 1-(2-chlorovinyl)benzene 
• 3947-94-2 (2-chloro-2-deuterio-vinyl)-benzene 
• 90740-04-8 1-α-1-chloro-2-phenylethyl acetate-d3 
• 384-64-5 3,3,3-trifluoro-2-phenylpropene 

Relevant academic research and scientific papers

1,1-Ethenediol: The Long Elusive Enol of Acetic Acid

We present the first spectroscopic identification of hitherto unknown 1,1-ethenediol, the enol tautomer of acetic acid. The title compound was generated in the gas phase through flash vacuum pyrolysis of malonic acid at 400 °C. The pyrolysis products were

Ortho-Deuteration of Aromatic Aldehydes via a Transient Directing Group-Enabled Pd-Catalyzed Hydrogen Isotope Exchange

A practical and scalable ortho-selective deuteration of aromatic aldehydes was accomplished by Pd-catalyzed hydrogen isotope exchange with deuterium oxide as an inexpensive deuterium source. The use of tert-leucine as a transient directing group facilitates the exchange, affording a wide range of ortho-deuterated aromatic aldehydes with deuterium incorporation up to 97%. The control experiments suggest that the addition of silver trifluoroacetate resists the unexpected reduction of Pd(II), while the theoretical study indicates a rapid reversible concerted metalation-deprotonation process.

Oxidative cleavage of the carbon-carbon σ-bond using reusable copper on iron

An efficient and resuble copper on iron catalyst has been prepared for the cleavage of the carbon-carbon σ-bond in α-aminocarbonyl compounds leading to the corresponding formylamides and acids with a maximal TON of up to 51,000. It is noteworthy that the copper on iron catalyst can be easily separated from the reaction mixture, and retains its activity after several reuses. Copyright