23735-46-8

Usage

Uses

Used in Flavoring Agents:
Ethanone, 1-bicyclo[2.2.2]oct-2-ylis used as a flavoring agent in the food industry, where it contributes to the creation of synthetic flavors and odors. Its strong odor makes it a valuable component in enhancing the sensory experience of various food products.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, Ethanone, 1-bicyclo[2.2.2]oct-2-ylis utilized in the synthesis of various pharmaceutical compounds. Its unique molecular structure offers potential for the development of new drugs and therapeutic agents, making it a valuable asset in medicinal chemistry research and development.
Used in Fragrance Production:
Due to its strong odor, Ethanone, 1-bicyclo[2.2.2]oct-2-ylis also employed in the production of synthetic fragrances. It can be incorporated into a wide range of scented products, from perfumes and colognes to household and personal care items, adding depth and complexity to their aroma profiles.

Upstream product

• 68569-32-4 bicyclo[2.2.2]octan-2-ylcarboxylic acid chloride 
• 40590-77-0 bicyclo(2.2.2)-5-octene-2-carboxaldehyde 
• 110-83-8 cyclohexene 
• 1165952-91-9 cyclohexa-1,3-diene 

Downstream Products

• 80605-53-4 Bicyclo<2.2.2>oct-2-ylmethylketonoximpikrat 
• 18684-63-4 bicyclo[2.2.2]octan-2-ol 

Relevant academic research and scientific papers

BTK INHIBITORS

Provided are Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions comprising these compounds and their use in therapy. In particular, provided is the use of Btk inhibitor compounds of Formula I in the treatment of Btk mediated disorders.

COMPOUNDS USEFUL AS MODULATORS OF TRPM8

The present invention includes compounds useful as modulators of TRPM8, such as compounds of Formulae (Ia), (Ib) and (Ic), and the subgenus and species thereof; personal products containing those compounds; and the use of those compounds and the personal products, particularly the use of increasing or inducing chemesthetic sensations, such as cooling or cold sensations.

Alkylwanderungen bei Sextettumlagerungen

The migration aptitude of alkyl groups in the Beckmann-, the Criegee-, and the isonitrile-nitrile rearrangements were investigated.The relative rearrangement rates of substituted benzyl groups are an expression of the charge on the migrating carbon at transition state.From the relative rates of migration of exo- and endo-2-norbornyl groups the geometrical changes at the migrating carbon is estimated.Finally, the different influence of α-branching in the migrating group is discussed for these and some other rearrangements.