23740-95-6Relevant articles and documents
Oxidative Recyclization of 1H-Indoles for Synthesis of 2-Indolylbenzoxazinones via Cleavage of the C2-C3 Bond with AIBN under Air
Liu, Xing-Xing,Luo, Xin-Liang,Wu, Zhao-Yang,Cui, Xin-Feng,Zhou, Xiao-Qiang,He, Yong-Qin,Huang, Guo-Sheng
, p. 2107 - 2113 (2017)
A novel and concise method for the oxidation of unprotected indole derivatives to synthesize 2-indolylbenzoxazinones in the presence of AIBN under open air has been successfully demonstrated. This metal-free reaction is both atom- and step-efficient and is applicable to a broad scope of substrates. This new methodology provides a facile pathway for oxidative C2-C3 bond cleavage and recyclization of 1H-indoles.