2376-43-4

Basic information

• Product Name: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl hexanoate
• Synonyms: 2-(4-(3-(2-(Trifluoromethyl)-10H-phenothiazin-10-yl)-propyl)-1-piperazinyl)ethyl hexanoate; Hexanoic acid, 2-(4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)-propyl)-1-piperazinyl)ethyl ester
• CAS NO: 2376-43-4
• Molecular Formula: C₂₈H₃₆F₃N₃O₂S
• Molecular Weight: 535.6645
• Mol File: 2376-43-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 619.7°C at 760 mmHg
• Flash Point: 328.6°C
• Density: 1.193g/cm³
• Vapor Pressure: 2.77E-15mmHg at 25°C
• Refractive Index: 1.546
• CAS DataBase Reference: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl hexanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl hexanoate(2376-43-4)
• EPA Substance Registry System: 2-(4-{3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl}piperazin-1-yl)ethyl hexanoate(2376-43-4)

Safety Data

• Hazardous Substances Data: 2376-43-4(Hazardous Substances Data)

Upstream product

• 142-61-0 Hexanoyl chloride 
• 69-23-8 Fluphenazine 

Relevant articles and documents

Esters of 4 [3 [2 (trifluoromethyl)phenothiazin 10 yl]propyl] 1 piperazineethanol and related compounds as long acting antipsychotic agents. Synthesis of the 1 adamantoate, the first crystalline base. 4

A number of new esters of fluphenazine are described; among these was the 1 adamantoate, 1h, the first highly crystalline ester of that drug. The 1 adamantoate of pipotiazine, 2b, typically, was an oil. Following a single subcutaneous or intramuscular injection of 25 mg/kg of either 1h or 2b, dissolved in sesame oil, each ester was found to be a potent and long acting inhibitor of conditioned avoidance behavior in the rat.