23761-24-2 Usage
General Description
3-Bromocyclobutanone is a chemical compound with the molecular formula C4H5BrO. It is a cyclic ketone that contains a bromine atom attached to a four-membered cyclobutanone ring. 3-Bromocyclobutanone is primarily used in organic synthesis and chemical research as a reagent and intermediate for the production of other organic compounds. It is also known to undergo various chemical reactions such as nucleophilic addition and ring-opening reactions due to the strain in the cyclobutanone ring. 3-Bromocyclobutanone has potential applications in the pharmaceutical and agrochemical industries due to its ability to participate in the synthesis of complex organic molecules. However, it is important to handle this compound with caution as it is potentially hazardous and can cause irritation and harm if not handled properly.
Check Digit Verification of cas no
The CAS Registry Mumber 23761-24-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,6 and 1 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 23761-24:
(7*2)+(6*3)+(5*7)+(4*6)+(3*1)+(2*2)+(1*4)=102
102 % 10 = 2
So 23761-24-2 is a valid CAS Registry Number.
InChI:InChI=1S/C4H5BrO/c5-3-1-4(6)2-3/h3H,1-2H2
23761-24-2Relevant articles and documents
Cyclobutenone as a highly reactive dienophile: Expanding upon diels-alder paradigms
Li, Xiaohua,Danishefsky, Samuel J.
, p. 11004 - 11005 (2010)
Cyclobutenone was employed as a dienophile in Diels-Alder cycloadditions, provide diverse and complex cycloadducts in good yields. Experimental outcomes indicated cyclobutenone to be more reactive than either cyclopentenone or cyclohexenone. In addition, cycloadducts bearing a strained cyclobutanone moiety were able to undergo regioselective ring expansions to produce corresponding cyclopentanones, lactones, and lactams, which are otherwise difficultly obtained by direct Diels-Alder reactions.
Preparation of cyclobutenone
Ross, Audrey G.,Li, Xiaohua,Danishefsky, Samuel J.
, p. 491 - 500 (2014/04/17)
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KINASE INHIBITORS AND METHODS OF USE
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Page/Page column 86-87, (2010/04/03)
The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating certain protein kinases such as mTor, tyrosine kinases, and/or lipid kinases such as PI3 kinase. Also provided in the present invention are methods of using these compositions to modulate activities of one or more of these kinases, especially for therapeutic applications.
