23761-52-6Relevant academic research and scientific papers
Elemental Sulfur-Promoted Aerobic Dehydrogenative Aromatization of Cyclohexanones with Amines
Wang, Zhen,Li, Cheng,Huang, Huawen,Deng, Guo-Jun
, p. 9415 - 9423 (2020/08/14)
An elemental sulfur-promoted aerobic dehydrogenation system for the access to N,N′-dialkyl-o-phenylenediamines and N-substituted 2-naphthylamines is reported herein. Readily available cyclohexanones and amines (especially alkylamines) are transformed smoo
N-(Pyridin-2-yl)benzamide: Efficient ligand for the nickel catalyzed Chan-Lam cross-coupling reaction
Keesara, Srinivas
, p. 6685 - 6688 (2016/01/28)
An efficient protocol for the Chan-Lam cross-coupling reactions of arylboronic acids with aryl or alkyl amines has been developed by employing simple N-(pyridin-2-yl)benzamide ligand with Ni(OAc)2·4H2O in the presence of TMG base. The reaction proceeded well with high yields by employing various N-nucleophiles at low catalytic loadings.
Aerobic oxidative homocoupling of aryl amines using heterogeneous rhodium catalysts
Matsumoto, Kenji,Dougomori, Kento,Tachikawa, Shohei,Ishii, Takanori,Shindo, Mitsuru
supporting information, p. 4754 - 4757 (2015/04/22)
The first heterogeneous catalyzed oxidative coupling of aryl amines is reported. Aryl amines were dimerized at room temperature under air using a heterogeneous Rh/C catalyst in the presence of acids. By choosing a suitable acidic solvent, biaryl compounds and carbazoles were selectively prepared in good yields. This reaction is operationally simple and provides an effi cient synthetic methodology for the preparation of biaryl diamines via oxidative C - H activation.
Nickel-catalyzed amination of aryl phosphates through cleaving aryl C-O bonds
Huang, Jin-Hua,Yang, Lian-Ming
supporting information; experimental part, p. 3750 - 3753 (2011/09/14)
The amination of triaryl phosphates was achieved using a Ni(II)-(σ-Aryl) complex/NHC catalyst system in dioxane at 110 °C in the presence of NaH as base. Electron-neutral, -rich, and -deficient triaryl phosphates were coupled with a wider range of amine partners including cyclic and acyclic secondary amines, aliphatic primary amines, and anilines in good to excellent yields.
Efficient copper-catalyzed N-arylations of nitrogen-containing heterocycles and aliphatic amines in water
Li, Xufeng,Yang, Daoshan,Jiang, Yuyang,Fu, Hua
experimental part, p. 1097 - 1105 (2010/08/06)
A simple and efficient copper-catalyzed method has been developed for N-arylations of nitrogen-containing heterocycles and aliphatic amines in water. The protocol uses (1E,2E)-oxalaldehyde dioxime (OADO) as the ligand, and water as the solvent, and shows good tolerance towards various functional groups.
Zinc-promoted, iridium catalyzed reductive alkylation of primary amines with aliphatic ketones in aqueous medium
da Silva, Renato A.,Bieber, Lothar W.
scheme or table, p. 689 - 691 (2010/04/02)
The reductive alkylation of primary aromatic and aliphatic amines with aliphatic ketones has been achieved in aqueous acidic medium using commercially available, non-activated zinc dust catalyzed by a very small quantity of iridium bromide. Anilines react well in aqueous formic acid, whereas monoalkylamines require 1,4-dioxane as a co-solvent and sulfuric acid as the proton source. A plausible mechanism via low-valent iridium hydride species is proposed.
Helicity of N,N′-diaryl-trans-1,2-diaminocyclohexane derivatives. Implications for molecular helicity manipulations
Kwit,Gawronski
, p. 9323 - 9331 (2007/10/03)
Derivatives of trans-1,2-diaminocyclohexane (DACH), useful as chiral ligands, scaffolds and building blocks, differ in their conformation. The conformation of N,N′-diaryl-DACH derivatives was studied by the semiempirical and DFT computational methods and by exciton-coupled circular dichroism. It was found that, contrary to M-helical N,N′-diimine, N,N′-diimide and N,N′-diamide derivatives, the aromatic residues in N,N′-diphenyl derivatives are oriented to form a P-helix for the (R,R)-DACH absolute configuration. The helicity of the bis-aryl system is modified in the case of 1-naphthyl or 2-naphthyl derivatives. Further switching of helicity has been demonstrated by either protonation or mono-N-acetylation of N,N′-diaryl DACH derivatives.
