23772-98-7Relevant articles and documents
A transition-metal-free & diazo-free styrene cyclopropanation
Herraiz, Ana G.,Suero, Marcos G.
, p. 9374 - 9379 (2019/10/22)
An operationally simple and broadly applicable novel cyclopropanation of styrenes using gem-diiodomethyl carbonyl reagents has been developed. Visible-light triggered the photoinduced generation of iodomethyl carbonyl radicals, able to cyclopropanate a wide array of styrenes with excellent chemoselectivity and functional group tolerance. To highlight the utility of our photocyclopropanation, we demonstrated the late-stage functionalization of biomolecule derivatives.