82665-91-6Relevant articles and documents
Decarboxylative (4+1) Oxidative Annulation of Malonate Monoesters with 2-Vinylpyridine Derivatives
Tang, Shan,Gao, Xinlong,Lei, Aiwen
, p. 2878 - 2882 (2016)
A novel N-iodosuccinimide-mediated decarboxylative (4+1) oxidative annulation between 2-vinylpyridine derivatives and malonate monoesters was developed. It offers a new way to construct indolizine derivatives by utilizing malonate monoesters as a C1unit. The alkyl 2,2-diiodoacetate was found to be the active reaction intermediate during the transformation. (Figure presented.).