237756-15-9Relevant academic research and scientific papers
Structure-activity relationship and rational design of 3,4-dephostatin derivatives as protein tyrosine phosphatase inhibitors
Watanabe, Takumi,Suzuki, Takayuki,Umezawa, Yoji,Takeuchi, Tomio,Otsuka, Masami,Umezawa, Kazuo
, p. 741 - 752 (2000)
Several alkyl- and O-methylated-3,4-dephostatin were synthesized and evaluated for their inhibitory activity toward protein tyrosine phosphatase. Alkyl chains with a length up to that of the pentyl group gave tolerable inhibition, whereas methylation of h
THIAZOLOPYRIDINONE DERIVATES AS MCH RECEPTOR ANTAGONISTS
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Page/Page column 47, (2008/06/13)
The present invention relates to a melanin concentrating hormone antagonist compound of formula (I); wherein w, R1, q, p, R2, t, Ar1, L1, R3 and R4 are as defined, or a pharmaceutically acceptable salt, solvate, or enantiomer thereof useful in the treatment, prevention or amelioration of symptoms associated with obesity and related diseases.
