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5-Hydroxytryptoline, also known as 5-HT, is a naturally occurring indole alkaloid derived from the dried fruit of Plectocorniopsis germinii Zorus. It is a carboline alkaloid present in the fruit at a concentration of 0.07 percent. The compound can be crystallized as a hydrochloride and sulfate, both with melting points above 300°C, as well as an acetate with a melting point of 293-295°C, a picrate with a melting point of 240°C, and an O,N-diacetyl derivative with a melting point of 168-170°C. The assigned structure of 5-hydroxytryptoline has been confirmed through spectroscopic data and demethylation of 6-methoxytetrahydro-(3-carboline) to yield the alkaloid.

23778-34-9

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23778-34-9 Usage

Uses

1. Used in Pharmaceutical Industry:
5-Hydroxytryptoline is used as an active pharmaceutical ingredient for the treatment of various medical conditions. It is particularly known for its role in the synthesis of serotonin, a neurotransmitter that plays a crucial role in regulating mood, appetite, and sleep. As a result, it has potential applications in the development of medications for depression, anxiety, and other mood disorders.
2. Used in Research and Development:
5-Hydroxytryptoline serves as an important compound in scientific research, particularly in the fields of neuroscience and pharmacology. It is used as a research tool to study the effects of serotonin on the central nervous system and to develop new drugs targeting the serotonin system.
3. Used in Dietary Supplements:
5-Hydroxytryptoline can be used as an ingredient in dietary supplements, particularly those aimed at improving mood, reducing stress, and promoting relaxation. It may also be used in combination with other ingredients to enhance their effects on mood and cognitive function.
4. Used in Cosmetics Industry:
In the cosmetics industry, 5-hydroxytryptoline may be used as an active ingredient in skincare products due to its potential benefits for mood regulation and stress reduction. This could lead to improved skin health and overall well-being.
5. Used in Food and Beverage Industry:
5-Hydroxytryptoline may also find applications in the food and beverage industry, where it could be used as a natural additive to enhance the mood-boosting properties of certain products. This could be particularly useful in the development of functional foods and beverages that promote mental well-being and relaxation.

References

Kiang, Chan, Taylor., Lloydia, 30, 189 (1967)

Check Digit Verification of cas no

The CAS Registry Mumber 23778-34-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,7,7 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 23778-34:
(7*2)+(6*3)+(5*7)+(4*7)+(3*8)+(2*3)+(1*4)=129
129 % 10 = 9
So 23778-34-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H12N2O/c14-7-1-2-10-9(5-7)8-3-4-12-6-11(8)13-10/h1-2,5,12-14H,3-4,6H2

23778-34-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-6-ol

1.2 Other means of identification

Product number -
Other names 6-Hydroxytetrahydronorharmane

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23778-34-9 SDS

23778-34-9Downstream Products

23778-34-9Relevant academic research and scientific papers

The chemistry of indoles. CVII. A synthesis of 3,4,5,6-tetrahydro-7-hydroxy-1H-azepino[5,4,3-cd]indoles and a new finding on pictet-spengler reaction

Somei,Teranishi,Yamada,Yamada

, p. 1159 - 1165 (2007/10/03)

Serotonins were found to produce 3,4,5,6-tetrahydro-7-hydroxy-1H-azepino[5,4,3-cd]indoles by simple heating with amines under an oxygen atmosphere. Serotonins also reacted with various aldehydes to provide 3,4,5,6-tetrahydro-7-hydroxy-1H-azepino[5,4,3-cd]

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