23786-93-8

Basic information

• Product Name: 1,1-diethoxycyclopentane
• Synonyms: 1,1-diethoxycyclopentane;1-Cyclopentanone diethyl acetal;Cyclopentanone diethyl acetal;Einecs 245-888-2
• CAS NO: 23786-93-8
• Molecular Formula: C₉H₁₈O₂
• Molecular Weight: 158.23802
• EINECS: 245-888-2
• Mol File: 23786-93-8.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 183°Cat760mmHg
• Flash Point: 49.6°C
• Appearance: /
• Density: 0.92g/cm³
• Vapor Pressure: 1.08mmHg at 25°C
• Refractive Index: 1.438
• CAS DataBase Reference: 1,1-diethoxycyclopentane(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-diethoxycyclopentane(23786-93-8)
• EPA Substance Registry System: 1,1-diethoxycyclopentane(23786-93-8)

Safety Data

• Hazardous Substances Data: 23786-93-8(Hazardous Substances Data)

Usage

Uses

1,1-Diethoxycyclopentane is a reagent that is used in the synthesis of Quinbolone (Q670150), which is a cyclopentenyl ether derivative of Boldenone (B675100) and also its active metabolite. Quinbolone shows weak androgenic activity.

Synthesis Reference(s)

Tetrahedron Letters, 32, p. 2429, 1991 DOI: 10.1016/S0040-4039(00)74345-0

InChI:InChI=1/C9H18O2/c1-3-10-9(11-4-2)7-5-6-8-9/h3-8H2,1-2H3

Upstream product

• 122-51-0 orthoformic acid triethyl ester 
• 120-92-3 cyclopentanone 
• 64-17-5 ethanol 
• 142-29-0 cyclopentene 

Downstream Products

• 90642-20-9 2-dimethylamino-cyclopent-1-enecarbaldehyde 
• 62041-55-8 2-((dimethylamino)methylene)cyclopentanone 
• 2882-93-1 C₁₉H₂₂O₂ 
• 108276-26-2 N-(8-Methyl-7-oxo-6,10-dioxa-spiro[4.5]dec-8-yl)-benzamide 
• 131087-26-8 (2S,3S,4R)-3-Benzyloxy-1,2-cyclopentylidenedioxy-4-hydroxyheptane 
• 931-20-4 1-methylpiperidin-2-one 
• 131087-27-9 (2S,3R,4R)-1,2-Cyclopentylidendioxy-3,4-dibenzyloxyheptane 
• 120-92-3 cyclopentanone 
• 156519-25-4 1-(2-ethoxycyclopent-1-enyl)-2,2,2-trifluoroethanone 
• 1097634-84-8 1-(1-ethoxycyclopentylperoxy)-1-hydroperoxycyclohexane 
• 1097634-91-7 1-(1-ethoxycyclopentylperoxy)-1-hydroperoxy-4-methylcyclohexane 
• 41164-59-4 hydroxypestalotin 
• 41164-59-4 (6R,1'S,2'R)-6-(1',2'-Dihydroxypentyl)-5,6-dihydro-4-methoxypyrane-2-one 
• 131087-31-5 (6RS,1'S,2'R)-6-(1',2'-Dibenzyloxypentyl)-5,6-dihydro-4-methoxypyrane-2-one 

Relevant articles and documents

2,3-dichloro-5,6-dicyano-p-benzoquinone (DDQ) as a highly efficient and mild catalyst for diethyl acetalization of carbonyl compounds

Various types of structurally different carbonyl compounds in the presence of ethyl orthoformate (EtO)3CH could be efficiently converted to their diethyl acetals by using a catalytic amount (1-3 mol%) of DDQ under mild reaction conditions.

Highly regioselective synthesis of trifluoromethyl derivatives of pyrazolo[1,5-a]pyrimidines bearing fused cycloalkane rings using (2-ethoxycycloalkenyl)-2,2,2-trifluoroethanones

8-Trifluoromethyl-6,7-dihydro-5H-1,4,8a-triaza-s-indacene and 9-trifluoromethyl-5,6,7,8-tetrahydropyrazolo[5,1-b]quinazolines were efficiently generated by condensation of 5(3)-aminopyrazoles with (2-ethoxycycloalkenyl)-2,2,2-trifluoroethanones and isolated in excellent yields. The regiochemistry of the prepared compounds was established by 1H, 13C and 19F NMR spectroscopy and X-ray diffraction analysis.

Bronsted acidic ionic liquids as efficient and recyclable catalysts for protection of carbonyls to acetals and ketals under mild conditions

A series of acidic ionic liquids have been used as efficient catalysts for the protection of various carbonyl compounds at room temperature. The features of mild conditions, satisfactory isolated yield, simple workup, and the recyclability of the catalyst were present in this process. Copyright Taylor & Francis, Inc.