23820-68-0

Upstream product

• 2515-09-5 (5R,6R)-5,6-Dibromo-17-(1,5-dimethyl-hexyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one 
• 57-88-5 cholesterol 
• 34026-89-6 cholesterin 

Relevant academic research and scientific papers

Stereoselective debromination and selective reduction of vic-dibromides with nickel boride

A simple procedure is reported for the stereoselective debromination of vic-dibromides with nickel boride at ambient temperature. Debromination with concomitant reduction of vic-dibromides to give dihydro products in a one-pot reaction is also reported. α,β-Dibromoketones can also be converted to their corresponding alcohols.

Structural elucidation, density functional calculations and contribution of intermolecular interactions in cholest-4-en-3-one crystals: Insights from X-ray and Hirshfeld surface analysis

The foremost objective of the present work is systematic analysis of intermolecular interactions in crystal structure of cholest-4-en-3-one (2) molecule. It is accomplished by Hirshfeld surface analysis and fingerprint plot. Hirshfeld surface analysis has been used to visualize the fidelity of the crystal structure. This method permitted for the identification of individual types of intermolecular contacts and their impact on the complete packing. Molecules are linked by a combination of CO - -H, CH - -H, and C - -H contacts, which have clear signatures in the fingerprint plots. The theoretical study was attempted to predict the optimized geometry and computed spectra by the Density Functional Theory (DFT) using the B3LYP function with the 6-311++G(d,p) basis set. Atomic charges, MEP mapping, HOMO-LUMO, various thermodynamic and molecular properties have been reported. In addition thermal stability, optical, morphological, and microstructral properties of the title compound (2) have also been explored.

DABCO-bis-CC: An efficient alternative to PCC

We have developed a new chromium based reagent ‘DABCO?bis-CC’ for the straightforward oxidation of alcohols to corresponding carbonyl compounds with high efficiency. The present results demonstrate a broad range of alcohols including primary, secondary, aliphatic, benzylic and heterocyclic alcohols are tolerated as substrates at room temperature.

A versatile cobalt(II)-Schiff base catalyzed oxidation of organic substrates with dioxygen: Scope and mechanism

Cobalt(II) complex 1a-f derived from Schiff bases act as efficient catalysts during the oxidation of wide range of organic substrates(e.g. alkenes, alcohols, benzylic compounds and aliphatic hydrocarbons) with dioxygen in the presence of aliphatic aldehydes or ketones or ketoesters. EPR studies on 1a-f complexes suggest that the aliphatic carbonyl compounds promote the formation of a cobalt(II)-superoxo species responsible for the oxidation of organic compounds. These studies also demonstrate the role of ligands on cobalt in controlling the chemoselectivity of these oxidations. A plausible mechanistic rational is also provided for these oxidations.

Heterogeneous Catalysis in Carbonyl Regeneration from 1,3-Dithiolanes and 1,3-Dithianes by Zirconium Sulfophenyl Phosphonate

Layered zirconium sulfophenyl phosphonate was found to be an efficient heterogeneous catalyst for mild hydrolysis of 1,2 dithiolanes and 1,3 dithianes to their corresponding carbonyl compounds.