23839-29-4Relevant academic research and scientific papers
TBD-catalyzed α-sulfenylation of cyclic ketones: Desymmetrization of 4-substituted cyclohexanones
Poladura, Belén,Martínez-Casta?eda, ángel,Rodríguez-Solla, Humberto,Concellón, Carmen,Del Amo, Vicente
experimental part, p. 6438 - 6446 (2012/08/28)
A low loading of triazabicyclo[4.4.0]dec-5-ene (TBD) catalyzes the α-sulfenylation reaction of ketones employing tetramethylthiuram disulfide (TMTDS) as electrophilic reagent. This methodology is mild, effective and straightforward, rendering the desired products in high yield. Prochiral 4-substituted cyclohexanones can be desymmetrized with remarkable diastereoselectivity following this protocol. The dithiocarbamoyl function was shown to be easily removed upon reduction, affording thiols (1-mercaptan-2-ols).
Direct organocatalytic -sulfenylation of aldehydes and ketones with tetramethylthiuram disulfide
Enders, Dieter,Rembiak, Andreas,Liebich, Jens X.
scheme or table, p. 281 - 286 (2011/03/18)
The direct pyrrolidine-catalyzed -sulfenylation of aldehydes and ketones with the commercially available, very cheap chemical tetramethylthiuram disulfide (thiram) is described. The dithiocarbamoyl derivatives are obtained in good to excellent yields (47-
ORGANOSULFUR TRANSFER WITH DISULFIDES IN THE PRESENCE OF CCl4
Wenschuh, Eberhard,Hesselbarth, Frank
, p. 133 - 136 (2007/10/02)
Thiols and protic nucleophiles undergo sulfur-element bond formation in the presence of CCl4/ base.Sulfenylation of CH-acidic compounds with thiols occur via disulfides, formed in a preliminary step.Uses and advantages of this organosulfur transfer are de
