238418-63-8

Basic information

• Product Name: D-Xylofuranose, 3-deoxy-3-fluoro- (9CI)
• Synonyms: D-Xylofuranose, 3-deoxy-3-fluoro- (9CI)
• CAS NO: 238418-63-8
• Molecular Formula: C5H9FO4
• Molecular Weight: 152.1209632
• Product Categories: HALIDE
• Mol File: 238418-63-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: D-Xylofuranose, 3-deoxy-3-fluoro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: D-Xylofuranose, 3-deoxy-3-fluoro- (9CI)(238418-63-8)
• EPA Substance Registry System: D-Xylofuranose, 3-deoxy-3-fluoro- (9CI)(238418-63-8)

Safety Data

• Hazardous Substances Data: 238418-63-8(Hazardous Substances Data)

Upstream product

• 18530-84-2 3-deoxy-3-fluoro-1,2-O-isopropylidene-α-D-xylofuranose 
• 70722-99-5 (3aR,5R,6S,6aS)-6-fluoro-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5-carbaldehyde 
• 18530-81-9 1-((3aR,5R,6S,6aS)-6-Fluoro-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-yl)-ethane-1,2-diol 
• 620630-82-2 1,2 5,6-O-di(isopropylidene)-α-D-allofuranose 

Downstream Products

• 129885-95-6 1-(3-deoxy-3-fluoro-β-D-xylofuranosyl)uracil 

Relevant articles and documents

MODIFIED RNAI AGENTS

One aspect of the present invention relates to double-stranded RNAi (dsRNA) duplex agent capable of inhibiting the expression of a target gene in vivo. The dsRNA duplex comprises one or more xylo modifications in one or both strand. Other aspects of the invention relates to pharmaceutical compositions comprising these dsRNA agents suitable for in vivo therapeutic use, and methods of inhibiting the expression of a target gene by administering these dsRNA agents, e.g., for the treatment of various disease conditions.