129885-95-6 Usage
General Description
3'-Deoxy-3'-fluoro-xylo-uridine is a chemical compound that belongs to the class of nucleoside analogs. It is an artificial nucleoside with a 3'-deoxy-3'-fluoro-xylofuranosyl substitution on the uridine base. 3'-Deoxy-3'-fluoro-xylo-uridine has potential pharmaceutical applications due to its ability to inhibit the replication of certain viruses, including HIV and hepatitis B virus. It is also being studied for its potential use in antiviral drug development and as a tool for studying nucleic acid structure and function. The unique structure of 3'-Deoxy-3'-fluoro-xylo-uridine makes it a promising candidate for further research and development in the field of antiviral therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 129885-95-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,8,8 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 129885-95:
(8*1)+(7*2)+(6*9)+(5*8)+(4*8)+(3*5)+(2*9)+(1*5)=186
186 % 10 = 6
So 129885-95-6 is a valid CAS Registry Number.
129885-95-6Relevant articles and documents
MODIFIED RNAI AGENTS
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Paragraph 0236, (2017/07/14)
One aspect of the present invention relates to double-stranded RNAi (dsRNA) duplex agent capable of inhibiting the expression of a target gene in vivo. The dsRNA duplex comprises one or more xylo modifications in one or both strand. Other aspects of the invention relates to pharmaceutical compositions comprising these dsRNA agents suitable for in vivo therapeutic use, and methods of inhibiting the expression of a target gene by administering these dsRNA agents, e.g., for the treatment of various disease conditions.
Diethylaminosulfur trifluoride (DAST) as a fluorinating agent of pyrimidine nucleosides having a 2',3'-vicinal diol system
Hayakawa,Takai,Tanaka,Miyasaka,Yamaguchi
, p. 1136 - 1139 (2007/10/02)
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