238420-38-7

Basic information

• Product Name: 2(1H)-Pyridinone, 1-(2-hydroxyethyl)-3-(phenylmethoxy)-
• CAS NO: 238420-38-7
• Molecular Formula: C14H15NO3
• Molecular Weight: 245.278
• Mol File: 238420-38-7.mol

Chemical Properties

• CAS DataBase Reference: 2(1H)-Pyridinone, 1-(2-hydroxyethyl)-3-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Pyridinone, 1-(2-hydroxyethyl)-3-(phenylmethoxy)-(238420-38-7)
• EPA Substance Registry System: 2(1H)-Pyridinone, 1-(2-hydroxyethyl)-3-(phenylmethoxy)-(238420-38-7)

Safety Data

• Hazardous Substances Data: 238420-38-7(Hazardous Substances Data)

Upstream product

• 880098-48-6 3-hydroxy-1-(2-hydroxyethyl)pyridin-2(1H)-one 
• 100-44-7 benzyl chloride 
• 20928-63-6 3-methoxy-1H-pyridin-2-one 
• 1402606-45-4 ethyl 2-(3-(benzyloxy)-2-oxopyridin-1(2H)-yl)acetate 
• 95215-70-6 1-ethoxycarbonylmethyl-3-hydroxy pyrid-2-one 
• 16867-04-2 dihydroxypyridine 
• 880098-46-4 1-(2-benzyloxyethyl)-3-methoxypyridin-2(1H)-one 
• 880098-47-5 1-(2-hydroxyethyl)-3-methoxypyridin-2(1H)-one 
• 95215-72-8 2-(3-(benzyloxy)-2-oxopyridin-1(2H)-yl)acetic acid 

Downstream Products

• 1248337-54-3 CH₃O₃S^(1-)*C₁₄H₁₄NO₂⁽¹⁺⁾ 
• 238420-43-4 25,27-bis-2-[2-(3-(benzyloxy)-2-oxo-1,2-dihydro-1-pyridyl)ethoxy]ethoxy-26,28-dihydroxy-p-tert-butylcalix[4]arene 
• 238420-41-2 3-(benzyloxy)-1-[2-(2-methanesulfonyloxyethoxy)ethyl]-2(1H)-pyridinone 
• 238420-40-1 3-(benzyloxy)-1-[2-(2-hydroxyethoxy)ethyl]-2-(1H)-pyridinone 
• 238420-42-3 3-(benzyloxy)-1-(2-(2-iodoethoxy)ethyl)pyridin-2(1H)-one 
• 816431-00-2 4(N),10(N)-bis[2-(3-benzyloxy-2-oxo-2H-pyridin-1-yl)ethyl]-1,7-dimethyl-1,4,7,10-tetraazacyclododecane 
• 880098-51-1 1,1,1-tris[carbonylethoxymethyl-7-amino-10,13-dioxaoctyl-16-(3'-benzyloxy-1',2'-dihydro-2'-oxopyridin-1'-yl)]ethane 
• 880098-50-0 1-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-3-benzyloxypyridine-2(1H)-one 
• 880098-49-7 1-{2-[2-(2-phthalimidoethoxy)ethoxy]ethyl}-3-benzyloxypyridine-2(1H)-one 
• 816430-99-6 3-(benzyloxy)-1-(2-chloroethyl)-1H-pyridin-2-one 
• 238420-39-8 3-(benzyloxy)-1-{2-[2-tetrahydro-2H-2-pyranyloxy]ethoxy}ethyl-2(1H)-pyridinone 

Relevant articles and documents

A practical route for the preparation of 1,4,7-triazacyclononanyl diacetates with a hydroxypyridinonate pendant arm

The preparation of triazamacrocyclic hydroxypyridinonate (HOPO-TACN) derivatives as potential chelators for metals in biomedical applications was reported. The synthesis is based on a convergent synthetic approach, in which the key intermediate di-tert-butyl-2,2′-(1,4,7-triazonane-1,4-diyl) diacetate was coupled with a hydroxypyridinonate pendant arm. The method is suitable for rapid syntheses of metal chelator HOPO-TACNs of biomedical interest.

Allosteric binding of alkali metal ions to a pseudocryptand formed by a C-pivot tripodal ligand containing 3-hydroxy-2(1H)-pyridinone and Ga(III)

A novel C-pivot tripodal hexadentate ligand (3,2-HOPOHL) composed of 3-hydroxy-2(1H)-pyridinone as a bidentate ligand, the ethyleneoxy chain as a spacer, and tris(carboxyric acid) as an anchor was synthesized. 3,2-HOPOHL recognized only Na+ ion, suggesting that it pre-organized a cavity due to the electrostatic interaction among the 2(1H)-pyridinone rings. UV-VIS spectroscopic analysis indicated that 3,2-HOPOHL formed a stable intramolecular 1:1 Fe(III) complex in aqueous solution. The stability constant (log K) of 3,2-HOPOHL-Fe(III) complex was estimated to be 27.6 from the competitive reaction with EDTA. 1H-NMR titration of 3,2-HOPOHL-Ga(III) complex with Na+ and K+ ions in CDCl3-CD3CN indicated the formation of 1:1 complexes. The binding constants of Na+- and K+-3,2-HOPOHL-Ga(III) complexes were estimated to be 3.3×103 and 7.8×103 M-1, respectively, the ion selectivity of K+ toward Na+ being more than two-fold.

Macrocyclic ligands bearing two 3-(hydroxy)-2-pyridinone moieties as side-arms. Conformational studies, synthesis, crystal structure, and alkali and alkaline earth complex formation

The synthesis and characterization of the new tetraazamacrocycle 4(N),10(N)-bis[2-(3-hydroxy-2-oxo-2H-pyridin-1-yl)ethyl]-1,7-dimethyl-1,4,7, 10-tetraazacyclododecane (L1) is reported. L1 shows two 3-(hydroxy)-1- (carbonylmethylen)-2(H)-pyridinone (HPO) m