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2,3-Dihydroxypyridine (DHP) is an organic compound characterized by the presence of two hydroxy groups at positions 2 and 3 on the pyridine ring. It appears as a khaki to grey or brown crystalline powder. DHP is known for its versatile chemical properties, which make it a valuable component in various applications across different industries.

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  • 16867-04-2 Structure
  • Basic information

    1. Product Name: 2,3-Dihydroxypyridine
    2. Synonyms: 2(1H)-Pyridinone, 3-hydroxy-;2(1H)-Pyridone, 3-hydroxy-;3-hydroxy-2(1h)-pyridinon;3-hydroxy-2(1H)-pyridinone;3-hydroxy-2(1h)-pyridon;PYRIDINE-2,3-DIOL;TIMTEC-BB SBB004333;2,3-DIHYDROXYPYRIDINE
    3. CAS NO:16867-04-2
    4. Molecular Formula: C5H5NO2
    5. Molecular Weight: 111.1
    6. EINECS: 240-887-3
    7. Product Categories: Pyridines, Pyrimidines, Purines and Pteredines;Pyridine;Pyridines derivates;Heterocyclic Compounds
    8. Mol File: 16867-04-2.mol
  • Chemical Properties

    1. Melting Point: 245 °C (dec.)(lit.)
    2. Boiling Point: 208.19°C (rough estimate)
    3. Flash Point: 245°C
    4. Appearance: khaki to grey or brown crystalline powder
    5. Density: 1.3113 (rough estimate)
    6. Vapor Pressure: 1.35E-07mmHg at 25°C
    7. Refractive Index: 1.4260 (estimate)
    8. Storage Temp.: Store below +30°C.
    9. Solubility: N/A
    10. PKA: 9.00±0.10(Predicted)
    11. Water Solubility: Soluble in water.
    12. BRN: 109848
    13. CAS DataBase Reference: 2,3-Dihydroxypyridine(CAS DataBase Reference)
    14. NIST Chemistry Reference: 2,3-Dihydroxypyridine(16867-04-2)
    15. EPA Substance Registry System: 2,3-Dihydroxypyridine(16867-04-2)
  • Safety Data

    1. Hazard Codes: Xi,Xn
    2. Statements: 36/37/38-40
    3. Safety Statements: 26-36-37/39-22
    4. WGK Germany: 3
    5. RTECS: UV1146700
    6. TSCA: Yes
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 16867-04-2(Hazardous Substances Data)

16867-04-2 Usage

Uses

Used in Chemical Synthesis:
2,3-Dihydroxypyridine is used as a key intermediate in the synthesis of various compounds. Its ability to form chelates with metal ions makes it a popular choice for creating macromolecular chelators, which are essential in various chemical processes.
2,3-Dihydroxypyridine is used as a chelating agent for [enhancing the stability and selectivity of metal ion complexes] in the synthesis of new macromolecular chelators by loading DHP on cellulose via linkers -NH-CH2-CH2-NH-SO2-C6H4-N=Nand -SO2-C6H4-N=N-.
Used in Amberlite XAD-2 Synthesis:
In the field of polymer chemistry, 2,3-Dihydroxypyridine is used as a component in the synthesis of DHP loaded amberlite XAD-2 via azo coupler. This application takes advantage of DHP's ability to form stable complexes with metal ions, which can be beneficial in various industrial processes.
2,3-Dihydroxypyridine is used as a component in [creating a metal ion complex with enhanced stability and selectivity] for the synthesis of DHP loaded amberlite XAD-2 via azo coupler.

Check Digit Verification of cas no

The CAS Registry Mumber 16867-04-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,8,6 and 7 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 16867-04:
(7*1)+(6*6)+(5*8)+(4*6)+(3*7)+(2*0)+(1*4)=132
132 % 10 = 2
So 16867-04-2 is a valid CAS Registry Number.
InChI:InChI=1/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)

16867-04-2 Well-known Company Product Price

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  • (Code)Product description
  • CAS number
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  • Alfa Aesar

  • (L07104)  2,3-Dihydroxypyridine, 98%   

  • 16867-04-2

  • 25g

  • 725.0CNY

  • Detail
  • Alfa Aesar

  • (L07104)  2,3-Dihydroxypyridine, 98%   

  • 16867-04-2

  • 100g

  • 2792.0CNY

  • Detail
  • Aldrich

  • (122505)  2,3-Dihydroxypyridine  95%

  • 16867-04-2

  • 122505-25G

  • 1,490.58CNY

  • Detail
  • Aldrich

  • (122505)  2,3-Dihydroxypyridine  95%

  • 16867-04-2

  • 122505-100G

  • 4,967.82CNY

  • Detail

16867-04-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-Dihydroxypyridine

1.2 Other means of identification

Product number -
Other names 2(1H)-Pyridinone, 3-hydroxy-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16867-04-2 SDS

16867-04-2Related news

Influence of mineral supplementation on 2,3-Dihydroxypyridine (cas 16867-04-2) toxicity in Angora goats07/27/2019

To study the effect of mineral supplementation on 2,3-DHP toxicity, 16 mature Angora wethers were randomly allocated to four treatment groups (M, DM, D and C). Two hours after the morning feeding; group M received a mineral mixture of 2 g of Fe2(SO4)3 · 7H20, 2 g of MgSO4 · 7H20 and 2 g of ZnS...detailed

Ionization effects on the sensitized photooxidation of 2,3-Dihydroxypyridine (cas 16867-04-2) and 2,4-dihydroxypyridine: a kinetic study07/23/2019

The kinetics of the Rose Bengal (RB)-sensitized photooxidation of 2,3-dihydroxypyridine (2,3-DHP) and 2,4-dihydroxypyridine (2,4-DHP), two compounds profusely employed in multiple fields such as pesticides design, pharmacology, and clinical therapeutics have been studied in water at pH 5, 11 and...detailed

16867-04-2Relevant articles and documents

DERMATOLOGICAL COMPOSITIONS AND METHODS

-

, (2008/06/13)

Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.

Treatment of neurodegenerative diseases

-

, (2008/06/13)

Disclosed are methods for increasing the differentiation of mammalian neuronal cells for purposes of treating neurodegenerative diseases or nerve damage by administration of various compounds including alcohols, diols and/or triols and their analogues.

Treatment of diseases mediated by the nitric oxide/cGMP/protein kinase G pathway

-

, (2008/06/13)

Disclosed are methods and compositions for stimulating cellular nitric oxide (NO) synthesis, cyclic guanosine monophosphate levels (cGMP), and protein kinase G (PKG) activity for purposes of treating diseases mediated by deficiencies in the NO/cGMP/PKG signal transduction pathway, by administration of various compounds including alcohols, diols and/or triols and their analogues.

Oxidation Reaction of 2- and 4-Hydroxypyridines

Ansari, M. Aslam

, p. 972 - 973 (2007/10/02)

Benzoyl peroxide reacts with 2-hydroxypyridine (I) in chloroform to give 3-benzoyloxy-2-hydroxypyridine (IIIa) and pyridine-2,3-dione (IV).However, with 4-hydroxypyridine (II) it gives 4,4',4''-trihydroxy-3,3',3''-terpyridyl (V) and trichloromethyl-4-hydroxypyridine (VI).The latter appears to have been formed by substitution in II with trichloromethyl radical produced from the interaction of benzoyl peroxide with chloroform.

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