23862-02-4

Basic information

• Product Name: 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL
• Synonyms: 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL;4(3H)-PyriMidinone, 2-(chloroMethyl)-6-Methyl-;2-(chloromethyl)-6-methyl-1H-pyrimidin-4-one
• CAS NO: 23862-02-4
• Molecular Formula: C6H7ClN2O
• Molecular Weight: 158.59
• Mol File: 23862-02-4.mol

Chemical Properties

• Boiling Point: 242.8 °C at 760 mmHg
• Flash Point: 100.6 °C
• Appearance: /
• Density: 1.37 g/cm³
• Vapor Pressure: 0.0332mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: 2-8°C
• PKA: 8.48±0.50(Predicted)
• CAS DataBase Reference: 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL(23862-02-4)
• EPA Substance Registry System: 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL(23862-02-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 23862-02-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL is used as an intermediate in the synthesis of various pharmaceutical compounds for its potential role in developing new drugs and therapeutic agents. Its unique structure allows for further chemical modifications, enabling the creation of diverse medicinal molecules.
Used in Agricultural Industry:
In the agricultural sector, 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL is utilized as an intermediate in the production of agrochemicals, such as pesticides and herbicides. Its chemical properties make it a valuable component in the development of effective and targeted crop protection solutions.
Used in Organic Synthesis:
2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL serves as a building block in organic synthesis, allowing chemists to create a wide range of organic compounds with various applications. Its functional groups and structural features facilitate the formation of new chemical entities for research and commercial purposes.
Used in Biological Research:
Due to its potential biological activity, 2-(CHLOROMETHYL)-6-METHYLPYRIMIDIN-4-OL may be employed in biological research to study its interactions with biological systems and explore its possible therapeutic effects. This can lead to the discovery of new bioactive molecules and a better understanding of their mechanisms of action.

InChI:InChI=1/C6H7ClN2O/c1-4-2-6(10)9-5(3-7)8-4/h2H,3H2,1H3,(H,8,9,10)

Upstream product

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Relevant articles and documents

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The invention relates to compounds of the formula (I) and to pharmaceutically acceptable salts, solvates, prodrugs and metabolites thereof, wherein W, Z, R1and R2, are as defined herein. The invention also relates to methods of treating Hepatitis C virus in mammals by administering the compounds of formula (I), and to pharmaceutical compositions for treating such disorders, which contain the compounds of formula (I). The invention also relates to methods of preparing the compounds of formula (I).

Organo-phosphoric esters and their production and use

Phosphoro-thioates or dithioates of the formula (I), STR1 wherein R is a C1 -C3 alkyl group, R1 is a C1 -C3 alkoxy, C1 -C4 alkylamino or allylamino group, R2 is a halogen atom, a C1 -C4 alkoxy or C1 -C3 alkyl group, R3 is a hydrogen or halogen atom or a C1 -C3 alkyl group, R4 is a C1 -C3 alkyl group, and X is an oxygen or sulfur atom, provided that when R1 is a C1 -C4 alkylamino or allylamino group, X is an oxygen atom, a process for producing phosphoro-thioates or dithioates of the formula (I) characterized by condensing a pyrimidine of the formula (II), STR2 wherein Y is a halogen atom, and R2, R3 and R4 are as defined above, with a thio- or dithio-phosphate of the formula, STR3 wherein M is an alkali metal atom or an ammonium group, and R, R1 and X are as defined above, an insecticide, acaricide and nematocide characterized by containing phosphoro-thioates or dithioates of the formula (I) as an active ingredient, and pyrimidines, novel intermediate compounds, of the formula (II) wherein R2 is a C1 -C4 alkoxy group or a halogen atom, R3 is a hydrogen or halogen atom or a C1 -C3 alkyl group, and R4 is a C2 -C3 alkyl group.