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1-phenyl-1,5,6,7-tetrahydro-indol-4-one, also known as tetrahydroharmane, is a chemical compound with a molecular formula C14H13NO. It is a tetrahydro derivative of harmane, a naturally occurring alkaloid found in various plants and animals. Tetrahydroharmane possesses diverse pharmacological properties, including potential psychoactive and neurotoxic effects, as well as its role in conditions such as Parkinson's disease and schizophrenia. Its ability to regulate dopamine and serotonin levels in the brain and bind to various receptors, including dopamine, serotonin, and opioid receptors, makes it an intriguing compound for further research and potential therapeutic applications.

23870-03-3

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23870-03-3 Usage

Uses

Used in Pharmaceutical Industry:
1-phenyl-1,5,6,7-tetrahydro-indol-4-one is used as a pharmaceutical candidate for its potential therapeutic applications in treating neurological and psychiatric disorders. Its diverse pharmacological properties, including modulation of dopamine and serotonin levels, as well as binding to various brain receptors, make it a promising compound for further research and development.
Used in Neurological Research:
1-phenyl-1,5,6,7-tetrahydro-indol-4-one is used as a research tool in the study of neurological conditions such as Parkinson's disease and schizophrenia. Its potential neurotoxic effects and involvement in the regulation of neurotransmitter levels provide valuable insights into the underlying mechanisms of these disorders and contribute to the development of novel therapeutic strategies.
Used in Drug Development:
1-phenyl-1,5,6,7-tetrahydro-indol-4-one is used in the development of new drugs targeting the dopamine and serotonin systems in the brain. Its ability to bind to various receptors, including dopamine, serotonin, and opioid receptors, offers potential for the creation of medications that can modulate these systems and treat related disorders.
Used in Toxicological Studies:
1-phenyl-1,5,6,7-tetrahydro-indol-4-one is used in toxicological research to investigate its potential neurotoxic effects and understand the mechanisms by which it may impact the brain. This research can contribute to the development of safer and more effective drugs with similar pharmacological properties.

Check Digit Verification of cas no

The CAS Registry Mumber 23870-03-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,8,7 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23870-03:
(7*2)+(6*3)+(5*8)+(4*7)+(3*0)+(2*0)+(1*3)=103
103 % 10 = 3
So 23870-03-3 is a valid CAS Registry Number.

23870-03-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-phenyl-1,5,6,7-tetrahydro-indol-4-one

1.2 Other means of identification

Product number -
Other names 1-Phenyl-4,5,6,7-tetrahydroindol-4-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23870-03-3 SDS

23870-03-3Relevant academic research and scientific papers

Microwave-assisted synthesis of tetrahydroindoles

Piras, Leonarda,Ghiron, Chiara,Minetto, Giacomo,Taddei, Maurizio

, p. 459 - 462 (2008/09/17)

An efficient synthesis of tetrahydroindoles with different substituents in position 1 is described. Microwave-assisted aminolysis of 4-oxo-4,5,6,7-tetrahydrobenzofuran with different primary amines gives the corresponding tetrahydroindoles in few minutes.

Copper-mediated N-arylation of electron-deficient pyrroles and indoles

Bekolo, Henri

, p. 42 - 46 (2008/02/03)

We have found that it is possible to N-arylate electron-deficient pyrroles and indoles having no carbonyl group a to the nitrogen ring in good to excellent yields under the Chan and Lam conditions using N-Ethyldiisopropylamine (DIEA) base as a substitute for triethylamine (TEA) and pyridine.

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