238756-53-1

Upstream product

• 152567-82-3 2-(5'-methyl-2'-thenoyl)benzoic acid 
• 85-44-9 phthalic anhydride 
• 554-14-3 2-Methylthiophene 

Downstream Products

• 439262-84-7 2-(5-methyl-2-thenyl)phenylacetic acid 
• 439262-82-5 2-(5-methyl-2-thenyl)benzyl bromide 
• 439262-80-3 2-(5-methyl-2-thenyl)benzyl alcohol 
• 80517-58-4 2-(2-Isocyanato-benzyl)-5-methyl-thiophene 

Relevant academic research and scientific papers

Synthesis of a benzo[5,6]cyclohepta[1,2-b]thiophene and thieno[3,2-c]-benzazepine derivatives

A new series of 2-methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[5,6]cyclohepta[1,2-b]thiophene (5) and 2-methyl-4-(4-methylpiperazin-1-yl)thieno[3,2-c][1]benzazepine derivatives 6b - f have been synthesized from 2-methylthiophene and phthalic anhydride. Preparation of the key intermediate 2-methyl-4,5-dihydro-10H-benzo[5,6]cyclohepta[1,2-b]thiophene-4-one (12) and 2-methylthieno[3,2-c][1]benzazepine-4(5H), 10-dione (16) were carried out by intramolecular dehydration of the phenylacetic acid 11 and Lewis acid associated cyclization of the isocyanate 14, respectively.

Cyclohepta[b]thiophene derivatives. Part-IV. Dehydrogenation of cyclohepta[b]thiophene and cyclohepta[c]thiophene derivatives

Cyclohepta[b]thiophenes 3 and cyclohepta[c]thiophene 4 on dehydrogenation with selenium give a complex mixture of dehydrogenated products. The formation of the identified products is explained through the initial homolytic cleavage at more than one particular bond in the cycloheptane moiety of 3 and 4. In all these cases ring contraction of the seven-membered ring of the thiophenes 3 and 4 is observed.