80517-58-4

Basic information

• Product Name: 2-(2-Isocyanato-benzyl)-5-methyl-thiophene
• CAS NO: 80517-58-4
• Molecular Weight: 229.302
• Mol File: 80517-58-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(2-Isocyanato-benzyl)-5-methyl-thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Isocyanato-benzyl)-5-methyl-thiophene(80517-58-4)
• EPA Substance Registry System: 2-(2-Isocyanato-benzyl)-5-methyl-thiophene(80517-58-4)

Safety Data

• Hazardous Substances Data: 80517-58-4(Hazardous Substances Data)

Upstream product

• 75-44-5 phosgene 
• 54451-56-8 2-(2-Aminobenzyl)-5-methylthiophen 
• 54397-35-2 (2-amino-phenyl)-(5-methyl-thiophen-2-yl)-methanone 
• 1885-29-6 anthranilic acid nitrile 
• 238756-53-1 2-(5'-methyl-2'-thenyl)benzoic acid 
• 152567-82-3 2-(5'-methyl-2'-thenoyl)benzoic acid 
• 85-44-9 phthalic anhydride 

Relevant articles and documents

Synthesis of a benzo[5,6]cyclohepta[1,2-b]thiophene and thieno[3,2-c]-benzazepine derivatives

A new series of 2-methyl-4-(4-methylpiperazin-1-yl)-10H-benzo[5,6]cyclohepta[1,2-b]thiophene (5) and 2-methyl-4-(4-methylpiperazin-1-yl)thieno[3,2-c][1]benzazepine derivatives 6b - f have been synthesized from 2-methylthiophene and phthalic anhydride. Preparation of the key intermediate 2-methyl-4,5-dihydro-10H-benzo[5,6]cyclohepta[1,2-b]thiophene-4-one (12) and 2-methylthieno[3,2-c][1]benzazepine-4(5H), 10-dione (16) were carried out by intramolecular dehydration of the phenylacetic acid 11 and Lewis acid associated cyclization of the isocyanate 14, respectively.