23876-76-8Relevant academic research and scientific papers
C-H...π and π-π interactions in the supramolecular structure of 3-methyl-1,4-diphenyl-1H-pyrazolo[3,4-b]-pyridine
Low, John N.,Cobo, Justo,Nogueras, Manuel,Sanchez, Adolfo,Torres, Harlen,Insuasty, Braulio
, p. o298-o300 (2002)
The supramolecular structure of the compound, C19H15N3, was investigated. The structure of the compound was defined by π-π-stacking and C-H···π interactions. The π-πstacking involved the pyridine ring of the pyrazolo-pyrid
A mild method for the synthesis of bis-pyrazolo[3,4-b:4′,3′-e]pyridine derivatives
Qiu, Rui,Qiao, Shujia,Peng, Boyu,Long, Jiajia,Yin, Guodong
supporting information, p. 3884 - 3888 (2018/09/27)
A mild and efficient method for the synthesis of bispyrazolo[3,4-b:4′,3′-e]pyridines from 5-aminopyrazoles and aromatic aldehydes using an inexpensive FeCl3 catalyst is reported. The reaction temperature was reduced from 220–250 °C to 130 °C compared to conventional methods. A large proportion of the products precipitated directly from the mixture at room temperature. Aliphatic and α,β-unsaturated aldehydes selectively resulted in formation of the corresponding 1H-pyrazolo[3,4-b]pyridine derivatives. A possible domino reaction mechanism was also proposed. Several aryl alkynyl groups were introduced to these tricyclic molecules via the Sonogashira coupling reaction.
