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Indolo[1,2-c]quinazoline is a heterocyclic compound consisting of a fused indole and quinazoline ring system. It is an important class of compounds due to its diverse range of biological activities, including antitumor, antiviral, and anti-inflammatory properties. The structure of indolo[1,2-c]quinazoline features a nitrogen atom at the 1-position of the indole ring and a nitrogen atom at the 2-position of the quinazoline ring, forming a bridge between the two rings. This unique structure allows for the formation of various derivatives with different functional groups, which can be further modified to enhance their pharmacological properties. The synthesis of indolo[1,2-c]quinazoline derivatives has been extensively studied, with various methods being developed to access these compounds, such as the condensation of o-aminophenyl derivatives with 2-aminobenzonitriles. Overall, indolo[1,2-c]quinazoline and its derivatives hold significant potential in the field of medicinal chemistry due to their promising therapeutic applications.

239-43-0

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239-43-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 239-43-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 2,3 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 239-43:
(5*2)+(4*3)+(3*9)+(2*4)+(1*3)=60
60 % 10 = 0
So 239-43-0 is a valid CAS Registry Number.

239-43-0Relevant academic research and scientific papers

Synthesis of indolo[1,2-c]quinazolines from 2-alkynylaniline derivatives through Pd-catalyzed indole formation/cyclization with N,N-dimethylformamide dimethyl acetal

Arcadi, Antonio,Cacchi, Sandro,Fabrizi, Giancarlo,Ghirga, Francesca,Goggiamani, Antonella,Iazzetti, Antonia,Marinelli, Fabio

, p. 2411 - 2417 (2018)

An efficient strategy for the synthesis of 6-unsubstituted indolo[1,2-c]quinazolines is described. The Pd-catalyzed reaction of o-(oaminophenylethynyl) trifluoroacetanilides with Ar-B(OH)2 afforded 2-(o-aminophenyl)-3-arylindoles, that were converted to 1

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