239094-83-8

Basic information

• Product Name: N'-[3-(1-benzenesulfonyl-1H-indol-2-yl)-6,7-dichloro-quinoxalin-2-yl]-N,N-diethyl-butane-1,4-diamine
• CAS NO: 239094-83-8
• Molecular Weight: 596.58
• Mol File: 239094-83-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N'-[3-(1-benzenesulfonyl-1H-indol-2-yl)-6,7-dichloro-quinoxalin-2-yl]-N,N-diethyl-butane-1,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N'-[3-(1-benzenesulfonyl-1H-indol-2-yl)-6,7-dichloro-quinoxalin-2-yl]-N,N-diethyl-butane-1,4-diamine(239094-83-8)
• EPA Substance Registry System: N'-[3-(1-benzenesulfonyl-1H-indol-2-yl)-6,7-dichloro-quinoxalin-2-yl]-N,N-diethyl-butane-1,4-diamine(239094-83-8)

Safety Data

• Hazardous Substances Data: 239094-83-8(Hazardous Substances Data)

Upstream product

• 239095-84-2 2,3-dibromo-6,7-dichloroquinoxaline 
• 25983-13-5 6,7-dichloro-1,4-dihydroquinoxaline-2,3-dione 
• 5348-42-5 4,5-Dichloro-1,2-phenylenediamine 
• 239095-87-5 N'-(3-bromo-6,7-dichloro-quinoxalin-2-yl)-N,N-diethyl-butane-1,4-diamine 

Relevant articles and documents

Synthesis and structure-activity relationship of 2-amino-3-heteroaryl-quinoxalines as non-peptide, small-molecule antagonists for interleukin-8 receptor

Interleukin-8 modulation is implicated in many inflammatory and cancer diseases. Starting from a mass-screening hit, the synthesis and structure-activity relationship of 2-amino-3-heteroarylquinoxalines as non-peptide, small molecule interleukine-8 receptor antagonists have been developed. The optimized derivatives, PD 0210293 (13y) and PD 0220245 (13r), show inhibition of both IL-8 receptor binding and IL-8-mediated neutrophil chemotaxis.