23911-64-0Relevant academic research and scientific papers
2D 1H and 13C NMR evidences of the [2+2] autodimerization of 2-benzyl-5-benzylidene cyclopentanone yielding two different diphenyl, dispiro cyclobutane derivatives
Diaz,Barrios,Corona,Guzman,Diaz,Fuentes
, p. 2079 - 2087 (2002)
The ene-ene [2+2] cycloaddition of 2-benzyl-5-benzylidenecyclopentanone proceeds smoothly and spontaneously in benzene-d6 or deuteriochloroform solution to give two different diphenyl dispiro [4.1.4.1] dodecan-4,11-diones. Detailed 1
Zinc mediated ring size tuned C=C reduction and C-C coupling of α,α′-(E,E)-bis(benzylidene)cycloalkanones
Kundu, Arijit,Bhattacharyya, Bhaswati,Dhara, Kaliprasanna,Patra, Amarendra
, p. 1711 - 1722 (2013/08/24)
Reduction of substituted α,α′-(E,E)-bis(benzylidene) cycloalkanones bearing five- and six-membered rings using zinc-amalgam in glacial acetic acid yielded C=C bond reduced products and C-C coupled compounds with the carbonyl functions remaining unaffected. Ring conformation exerted pronounced influence on the extent of reduction. The diastereomerism around the coupled benzylic carbons and the relative orientations of the like groups varied with the central cycloalkanone ring types. OFT studies indicated conformational differences between the substrates of two cyclic systems and consequently the ease of electron transfer from metal to them would vary. Dimeric molecules exhibited their associative properties involving π-π interactions and intermolecular H-bond formation.
Synthesis, antiinflammatory, and cytotoxic activities of 2-alkyl and 2-benzyl-2-dimethylaminomethyl-5-(E)-arylidene cyclopentanone hydrochlorides
Chen, Haitao,Ji, Zhizhong,Wong, Lan K.,Siuda, Jerome F.,Narayanan, Ven L.
, p. 1482 - 1487 (2007/10/03)
Purpose. A series of 2-substituted-2-dimethylaminomethyl-5-(E)-arylidene cyclopentanones, 4 were synthesized. The main objective of this investigation was to explore the structural parameters necessary for antiinflammatory activity in this series of compo
