2392-98-5 Usage
General Description
Salutaridinol is an organic chemical compound that is commonly associated with plants, particularly those of the Papaveraceae family which includes poppy plants. It is an alkaloid and critical intermediate in the biosynthetic pathway leading to the formation of several pharmacologically important compounds such as morphine and codeine. The compound is biosynthesized from reticuline and its derivatization leads to the formation of salutaridine, another central compound in the synthesis pathway of morphine and codeine. Discovered in the late 20th century, salutaridinol continues to be a subject of study due to its key intermediary role in the production of important pharmaceutical opioid compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 2392-98-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,9 and 2 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 2392-98:
(6*2)+(5*3)+(4*9)+(3*2)+(2*9)+(1*8)=95
95 % 10 = 5
So 2392-98-5 is a valid CAS Registry Number.
2392-98-5Relevant articles and documents
A Regio- and Diastereoselective Anodic Aryl–Aryl Coupling in the Biomimetic Total Synthesis of (?)-Thebaine
Lipp, Alexander,Ferenc, Dorota,Gütz, Christoph,Geffe, Mario,Vierengel, Nina,Schollmeyer, Dieter,Sch?fer, Hans J.,Waldvogel, Siegfried R.,Opatz, Till
supporting information, p. 11055 - 11059 (2018/08/21)
The biosynthesis of thebaine is based on the regioselective, intramolecular, oxidative coupling of (R)-reticuline. For decades, chemists have sought to mimic this coupling by using stoichiometric oxidants. However, all approaches to date have suffered from low yields or the formation of undesired regioisomers. Electrochemistry would represent a sustainable alternative in this respect but all attempts to accomplish an electrochemical synthesis of thebaine have failed so far. Herein, a regio- and diastereoselective anodic coupling of 3′,4′,5′-trioxygenated laudanosine derivatives is presented, which finally enables electrochemical access to (?)-thebaine.
INVESTIGATIONS ON THE BIOSYNTHESIS OF MORPHINE ALKALOIDS.
BARTON,KIRBY,STEGLICH,THOMAS,BATTERSBY,DOBSON,RAMUZ
, p. 2423 - 2438 (2007/10/04)
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