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(3a,5b,6b,7b)-3,6,7-trihydroxy-Cholan-24-oic acid, also known as β-Muricholic Acid (β-MCA), is a murine-specific primary bile acid derived from the cholesterol molecule. It is characterized by its unique structural features, including the presence of three hydroxyl groups at the 3, 6, and 7 positions, and a carboxylic acid group at the 24th position. This bile acid plays a crucial role in the regulation of cholesterol metabolism and has been found to have potential applications in various fields due to its unique properties.

2393-59-1

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2393-59-1 Usage

Uses

1. Used in Cholesterol Metabolism Regulation:
β-Muricholic Acid is used as a regulator of cholesterol metabolism for its ability to reduce HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. This application is significant in managing and treating conditions related to high cholesterol levels.
2. Used in Gallstone Treatment:
β-Muricholic Acid is used as a therapeutic agent for gallstone treatment, as it has been shown to dissolve 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones. This application highlights its potential in addressing gallstone-related health issues.
3. Used in Protein Regulation Studies:
β-Muricholic Acid has been utilized in research for its role in the downregulation of transporter protein through ubiquitin-dependent protein degradation. This application is valuable in understanding the molecular mechanisms underlying various biological processes and diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 2393-59-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,9 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2393-59:
(6*2)+(5*3)+(4*9)+(3*3)+(2*5)+(1*9)=91
91 % 10 = 1
So 2393-59-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H40O5/c1-13(4-7-19(26)27)15-5-6-16-20-17(9-11-23(15,16)2)24(3)10-8-14(25)12-18(24)21(28)22(20)29/h13-18,20-22,25,28-29H,4-12H2,1-3H3,(H,26,27)/t13?,14-,15?,16?,17?,18+,20?,21+,22-,23-,24-/m1/s1

2393-59-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name (3α,5β,6β,7β)-3,6,7-Trihydroxycholan-24-oic acid

1.2 Other means of identification

Product number -
Other names 2-Cyan-3-(3-methylphenyl)-2-butensaeure-ethylester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2393-59-1 SDS

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