23938-42-3Relevant academic research and scientific papers
One-pot dichlorinative deamidation of primary β-ketoamides
Zheng, Congke,Zhang, Xiaohui,Ijaz Hussain, Muhammad,Huang, Mingming,Liu, Qing,Xiong, Yan,Zhu, Xiangming
, p. 574 - 577 (2017/01/16)
An approach to the dichlorinative deamidation of primary β-ketoamides through ketonic cleavage is described, and a series of α,α-dichloroketones were furnished mostly in the presence of TEMPO. Based on control experiments, a mechanism involving tandem dichlorination and deamidation is proposed to interpret the observed reactivity.
Reactions of methyl esters of adamantane acids with acetonitrile
Shiryaev,Belen′kaya,Shiryaev,Rybakov,Klimochkin, Yu. N.
, p. 2966 - 2969 (2016/09/28)
Methyl adamantane-1-carboxylate and methyl (1-adamantyl)acetate react with acetonitrile in the presence of sodium hydride to give 3-(1-adamantyl)-3-oxopropanenitrile and 4-(1-adamantyl)-3-oxobutanenitrile, respectively. Reaction involving methyl (1-adamantyl)-acetate produces also 2-(1-adamantyl)-N-(E-1-cyanoprop-1-ene-2-yl)acetamide; the structure of this side product was established by X-ray diffraction analysis.
P38 MAP KINASE INHIBITORS
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Page/Page column 54, (2011/10/31)
There is provided a compound of formula (I): wherein: J represents (A): or (B): compositions comprising same, processes for preparing said compounds and use thereof in treatment, particularly in the treatment of inflammatory disease, such as asthma, COPD and 15 rheumatoid arthritis.
Photographic material and process comprising a pyrazolotriazole coupler
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, (2008/06/13)
Novel 1H-pyrazolo[1,5-b]1,2,4 triazole couplers containing in the 6- position an unsubstituted or substituted multicyclic hydrocarbon group, eg an adamantyl group, in a photographic material and process enable dye images that exhibit improved light stability. These couplers are useful in photographic materials and processes.
