23942-11-2 Usage
General Description
2-amino-5-benzyl-6-methyl-1H-pyrimidin-4-one, also known as benzylmethylaminouracil, is a chemical compound that belongs to the class of pyrimidine derivatives. It is a heterocyclic compound with a pyrimidine ring structure, which contains an amino group at the 2-position, a benzyl group at the 5-position, and a methyl group at the 6-position. 2-amino-5-benzyl-6-methyl-1H-pyrimidin-4-one has been studied for its potential pharmaceutical applications, particularly as a building block for the synthesis of various bioactive molecules and pharmaceuticals. It may also have potential use in the field of medicinal chemistry and drug discovery due to its unique structural features and potential biological activities.
Check Digit Verification of cas no
The CAS Registry Mumber 23942-11-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,9,4 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 23942-11:
(7*2)+(6*3)+(5*9)+(4*4)+(3*2)+(2*1)+(1*1)=102
102 % 10 = 2
So 23942-11-2 is a valid CAS Registry Number.
23942-11-2Relevant articles and documents
Direct synthesis of 5- and 6-substituted 2-aminopyrimidines as potential non-natural nucleobase analogues
Radhakrishnan,Sharma, Namita,Kundu, Lal Mohan
, p. 15087 - 15090 (2014/04/17)
A series of 2-aminopyrimidine derivatives, substituted at 5- and 6-positions, were synthesized. The reaction was carried out in a single step by treatment of the corresponding β-ketoester or β-aldehydoester with guanidine hydrochloride in the presence of K2CO3, in a microwave-assisted method without the requirement of solvent. A unique 1:1 co-crystal structure was obtained which shows that a 6-phenyl-2- aminopyrimidinone forms a strong nucleobase-pair with cytosine, involving three hydrogen bonds. The base-pair was found to be as strong as that of natural guanine:cytosine (G:C), signifying the potential application of the synthesized derivatives. Additionally, we also report a second co-crystal involving 5-isopropyl-6-methyl-2-aminopyrimidinone and cytosine in a 1:1 ratio, which also shows strong base-pairing properties. the Partner Organisations 2014.
